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In the Clouds

  • Mark T. Friedman
  • Kamille A. West
  • Peyman Bizargity
  • Kyle Annen
  • Jeffrey S. Jhang
Chapter

Abstract

A 10-year-old boy presents with a history of multiple recurrent infections including pneumonia, lymphadenitis, and osteomyelitis since the age of 2 months. The patient currently has a pulmonary mycetoma that is refractory to medical treatment and is scheduled for surgical resection. A type and screen sample (ethylenediaminetetraacetic acid [EDTA] anticoagulant) is submitted to the blood bank with a request for two units of red blood cells (RBCs) for surgery.

Keywords

Acanthocytes Anti-Km antibody Anti-Kx antibody Creatine kinase Chronic granulomatous disease gp91phox gene Kell blood group Kell null McLeod syndrome 

References

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    Storry JR. Other blood group systems and antigens. In: Fung MK, Grossman BJ, Hillyer CD, Westhoff CM, editors. Technical manual. 18th ed. Bethesda: AABB; 2014. p. 348.Google Scholar
  2. 2.
    Allen FH, Krabbe SMR, Corcoran PA. A new phenotype (McLeod) in the Kell blood-group system. Vox Sang. 1961;6:555–60.CrossRefPubMedGoogle Scholar
  3. 3.
    Watkins CE, Litchfield J, Song E, Jaishankar GB, Misra N, Holla N, et al. Chronic granulomatous disease, the McLeod phenotype and the contiguous gene deletion syndrome-a review. Clin Mol Allergy. 2011;9:13.CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Mark T. Friedman
    • 1
  • Kamille A. West
    • 2
  • Peyman Bizargity
    • 3
  • Kyle Annen
    • 4
  • Jeffrey S. Jhang
    • 1
  1. 1.Icahn School of MedicineMount Sinai Health SystemNew YorkUSA
  2. 2.Department of Transfusion MedicineNational Institutes of Health Clinical CenterBethesdaUSA
  3. 3.Department of Molecular & Human GeneticsBaylor College of MedicineHoustonUSA
  4. 4.Department of PathologyChildren’s Hospital ColoradoAuroraUSA

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