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What’s This Junk?

  • Mark T. Friedman
  • Kamille A. West
  • Peyman Bizargity
  • Kyle Annen
  • Jeffrey S. Jhang
Chapter

Abstract

A 53-year-old man, with history of coronary artery disease, hypertension, type 2 diabetes mellitus, and chronic anemia, presents with gangrenous left foot and is scheduled for amputation. The patient was transfused with red blood cells (RBCs) at the hospital 3 years ago and most recently 6 months ago; the antibody screen was negative at those times. A type and screen sample (ethylenediaminetetraacetic acid [EDTA] anticoagulant) is submitted to the blood bank.

Keywords

Bennett–Goodspeed/Bg Chido–Rodgers Dithiothreitol/DTT Ficin High-titer/low-avidity antibody/HTLA Knops system Trypsin 

Reference

  1. 1.
    Moulds JM. The knops blood group system: a review. Immunohematology. 2010;26(1):2–7.PubMedGoogle Scholar

Recommended Reading

  1. Reid ME, Lomas-Francis C, Olsson ML. Knops blood group system. In: Reid ME, Lomas-Francis C, Olsson ML, editors. The blood group antigen facts book. 3rd ed. London: Elsevier; 2012. p. 549–55.CrossRefGoogle Scholar
  2. Rolih S. A review: antibodies with high-titer, low avidity characteristics. Immunohematology. 1990;6:59–67.PubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Mark T. Friedman
    • 1
  • Kamille A. West
    • 2
  • Peyman Bizargity
    • 3
  • Kyle Annen
    • 4
  • Jeffrey S. Jhang
    • 1
  1. 1.Icahn School of MedicineMount Sinai Health SystemNew YorkUSA
  2. 2.Department of Transfusion MedicineNational Institutes of Health Clinical CenterBethesdaUSA
  3. 3.Department of Molecular & Human GeneticsBaylor College of MedicineHoustonUSA
  4. 4.Department of PathologyChildren’s Hospital ColoradoAuroraUSA

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