The Transfusion Reaction
A 38-year-old man who underwent craniotomy surgery 2 months ago presents for outpatient red blood cell (RBC) transfusion of two units for symptomatic anemia and hemoglobin (Hgb) level of 7.4 g/dL. The patient had received multiple RBC transfusions during the craniotomy surgery and postoperatively in recovery; all of the RBC units were issued by immediate-spin (IS) crossmatch. A type and screen sample (ethylenediaminetetraacetic acid [EDTA] anticoagulant) is submitted to the blood bank along with a request for the two units of RBCs.
KeywordsAnti-Dia antibody Anti-Goa antibody Delayed hemolytic transfusion reaction Diego blood group system Febrile non-hemolytic transfusion reaction Septic transfusion reaction Transfusion reaction Transfusion-associated graft-versus-host disease/GVHD