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Basic Single Antibody Identification: How Hard Can It Be?

  • Mark T. Friedman
  • Kamille A. West
  • Peyman Bizargity
  • Kyle Annen
  • Jeffrey S. Jhang
Chapter

Abstract

A 52-year-old man with a history of hypertension, type 2 diabetes mellitus, and three-vessel coronary artery disease is admitted to the hospital for a coronary artery bypass graft (CABG) surgery. An ethylenediaminetetraacetic acid (EDTA) anticoagulant sample is submitted to the blood bank for type and screen along with an order for four units of red blood cells (RBCs). No transfusion history is given.

Keywords

ABO blood group Anti-E antibody E antigen Rh antibodies Rh blood group Warm-reacting alloantibody 

Reference

  1. 1.
    Walker PS, Hamilton JR. Identification of antibodies to red cell antigens. In: Fung MK, Grossman BJ, Hillyer CD, Westhoff CM, editors. Technical manual. 18th ed. Bethesda: AABB; 2014. p. 398–400.Google Scholar

Recommended Reading

  1. Avent ND, Reid ME. The Rh blood group system: a review. Blood. 2000;95:375–87.PubMedGoogle Scholar
  2. Trudell KS. Detection and identification of antibodies. In: Harmening DM, editor. Modern blood banking and transfusion practices. 6th ed. Philadelphia: F.A. Davis; 2012. p. 216–26.Google Scholar
  3. Walker PS, Hamilton JR. Identification of antibodies to red cell antigens. In: Fung MK, Grossman BJ, Hillyer CD, Westhoff CM, editors. Technical manual. 18th ed. Bethesda: AABB; 2014. p. 391–421.Google Scholar
  4. Dean L. Blood groups and red cell antigens National Center for Biotechnology Information (NCBI), National Library of Medicine, National Institutes of Health, Bethesda, MD 20892- 6510. Bethesda: National Center for Biotechnology Information (US; 2005.Google Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Mark T. Friedman
    • 1
  • Kamille A. West
    • 2
  • Peyman Bizargity
    • 3
  • Kyle Annen
    • 4
  • Jeffrey S. Jhang
    • 1
  1. 1.Icahn School of MedicineMount Sinai Health SystemNew YorkUSA
  2. 2.Department of Transfusion MedicineNational Institutes of Health Clinical CenterBethesdaUSA
  3. 3.Department of Molecular & Human GeneticsBaylor College of MedicineHoustonUSA
  4. 4.Department of PathologyChildren’s Hospital ColoradoAuroraUSA

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