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Outcomes Following Acute Kidney Injury in Children

  • Scott M. Sutherland
Chapter

Abstract

Over the past decade, the Nephrology and Critical Care communities have adopted a consensus approach to the diagnosis of acute kidney injury (AKI). This has led to transformative changes in our understanding of AKI epidemiology in both adults and children. As such, our knowledge regarding the short- and long-term outcomes among children who develop AKI has become far more robust. The best available data suggest that AKI is associated with the need for mechanical ventilation, prolonged hospital stays, and higher mortality. Though AKI was originally thought to be self-limited, we now know that renal recovery is far from universal, particularly in the setting of severe AKI. Additionally, AKI survivors, especially those without full recovery, are at risk for chronic renal sequelae including proteinuria, hypertension, and chronic kidney disease. This chapter comprehensively describes AKI-related outcomes in children and focuses on identifying the independent effects of these events.

Keywords

Acute kidney injury AKI Outcomes Renal recovery Mortality Chronic kidney disease Children 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of Nephrology, Department of PediatricsStanford UniversityStanfordUSA

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