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Phototherapy and Photochemotherapy

  • James L. Griffith
  • Allison J. Zarbo
  • Henry W. Lim
Chapter
Part of the Updates in Clinical Dermatology book series (UCD)

Abstract

Phototherapy and photochemotherapy have remained cornerstones in the management of psoriasis and other cutaneous conditions for more than 3000 years. Currently, ultraviolet (UV)-based therapy is one of the first-line therapies for psoriasis due to its high response rate, relative low cost, and minimal generalized immunosuppression compared to other systemic therapies. This chapter will outline the basic principles of photomedicine and photochemistry before delving into the evidence behind the use of current and emerging UV, laser, and light therapies in psoriasis. Practical considerations, such as their indications, contraindications, administration, combination therapies, relevant adverse effects, and application in special populations (pregnancy, pediatrics, and those without access to in-office treatment), will also be discussed.

Keywords

Phototherapy Photochemotherapy Psoriasis Blue light Narrowband ultraviolet B (NB-UVB) Psoralen plus ultraviolet A (PUVA) Goeckerman Pulsed dye laser (PDL) Intense pulsed light (IPL) Photodynamic therapy (PDT) 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • James L. Griffith
    • 1
  • Allison J. Zarbo
    • 1
  • Henry W. Lim
    • 1
  1. 1.Department of DermatologyHenry Ford HospitalDetroitUSA

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