Enteroviruses are a large group of viruses that are capable of causing a variety of clinical diseases in infants. Infections can be acquired congenitally or, more commonly, through postnatal contact with stool or respiratory secretions from an infected individual. Asymptomatic or nonspecific illnesses are most common, but more severe infections such as sepsis, meningoencephalitis, myocarditis, and more can result. Preterm infants or those with disease onset in the first week of life are at highest risk. Mortality is largely determined by the clinical presentation, with myocarditis and encephalitis causing the highest mortality. In addition to supportive care, intravenous immunoglobulin may be beneficial if it contains sufficient amount of neutralizing antibody for the serotype of enterovirus causing the infection.
KeywordsEncephalitis Enterovirus Intravenous immunoglobulin Meningitis Myocarditis
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