Hemodynamic Effects of Mechanical Ventilation

  • Hooman Poor


Critically ill patients that require mechanical ventilation often have concomitant hemodynamic instability. The direct hemodynamic effects of mechanical ventilation can further complicate their condition. Specifically, increases in intrathoracic pressure due to positive pressure ventilation can significantly impact cardiac function. It is therefore crucial to understand this interaction in order to minimize any untoward effects of mechanical ventilation.


Stroke volume Cardiac output Arterial oxygen content Oxygen delivery Preload Preload sensitive Preload insensitive Afterload Wall stress Transmural pressure 

Suggested Readings

  1. 1.
    Mann D, Zipes D. Braunwald’s heart disease: a textbook of cardiovascular medicine. 10th ed. Philadelphia: Saunders; 2009.Google Scholar
  2. 2.
    Cairo J. Pilbeam’s mechanical ventilation: physiological and clinical applications. 5th ed. St. Louis: Mosby; 2012.Google Scholar
  3. 3.
    Costanzo L. Physiology. 5th ed. Beijing: Saunders; 2014.Google Scholar
  4. 4.
    MacIntyre N, Branson R. Mechanical ventilation. 2nd ed. Philadelphia: Saunders; 2009.Google Scholar
  5. 5.
    Marino P. Marino’s the ICU book. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2007.Google Scholar
  6. 6.
    Poor H, Ventetuolo C. Pulmonary hypertension in the intensive care unit. Prog Cardiovasc Dis. 2012;55(2):187–98.CrossRefPubMedGoogle Scholar
  7. 7.
    Rhoades R, Bell D. Medical physiology: principles for clinical medicine. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2013.Google Scholar
  8. 8.
    Tobin M. Principles and practice of mechanical ventilation. 3rd ed. Beijing: McGraw-Hill; 2013.Google Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Hooman Poor
    • 1
  1. 1.Mount Sinai – National Jewish Health Respiratory InstituteIcahn School of MedicineNew YorkUSA

Personalised recommendations