Imaging of Non-thymic Anterior Mediastinal Tumors

  • Roy A. RaadEmail author


The mediastinum contains a variety of vital structures and organs, including the thymus, lymph nodes, adipose tissues, vascular structures, nerves, and esophagus, all of which can give rise to various masses and other nonneoplastic abnormalities. Imaging is the integral part of the workup for mediastinal tumors, specifically chest computed tomography (CT) and in equivocal cases magnetic resonance imaging (MRI), leading in many cases to a confident presumptive diagnosis, even without necessitating biopsy, surgery, or other confirmatory testing.

In this chapter, we focus on discussing the clinical manifestations, diagnosis, and treatment of non-thymic tumors, specifically germ cell tumors, lymphoma, and mesenchymal tumors. Although this is discussed in prior chapters, we start by discussing a generalized structured imaging approach that radiologists can use when evaluating anterior mediastinal tumors in general, aided by useful clinical and laboratory information when made available. Thymic benign and malignant tumors are discussed in detail in other chapters.


Anterior mediastinum Chest CT Chest MR FDG PET/CT Lymphoma Seminoma Teratoma Nonseminomatous germ cell tumor Mesenchymal tumor 





Complete blood count


Computed tomography


Erythrocyte sedimentation rate




Germ cell tumor


Hodgkin’s lymphoma


Hounsfield units


Large B-cell lymphoma


Lactate dehydrogenase


Magnetic resonance imaging


Positron-emission tomography/computed tomography


Superior vena cava


Beta-human chorionic gonadotropin


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of RadiologyNew York University School of MedicineNew YorkUSA
  2. 2.Department of RadiologySt. George Hospital University Medical CenterBeirutLebanon

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