Thyroid Fine Needle Aspiration Cytology
Fine needle aspiration (FNA) is the procedure of choice in the management of thyroid nodules in an appropriate clinical setting. The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) has been widely used while evaluating thyroid FNA specimens and communicating the findings with the clinicians who treat patients. This chapter includes 90 images demonstrating key cytologic features of common and uncommon thyroid entities outlined in TBSRTC. The role of ancillary studies as an adjunct to FNA cytology is discussed.
KeywordsThyroid Fine needle aspiration FNA Bethesda system Benign thyroid nodule Malignant thyroid nodule Atypia of undetermined significance Follicular lesion of undetermined significance AUS/FLUS
The author thanks Brian Smola, senior cytotechnologist at the University of Michigan, for proofreading and editing the chapter.
- 9.Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid Cancer. Thyroid. 2016;26:1–133.CrossRefPubMedPubMedCentralGoogle Scholar
- 13.Faquin WC, Wong LQ, Afrogheh AH, Ali SZ, Bishop JA, Bongiovanni M, et al. Impact of reclassifying noninvasive follicular variant of papillary thyroid carcinoma on the risk of malignancy in the Bethesda system for reporting thyroid cytopathology. Cancer Cytopathol. 2016;124:181–7.CrossRefPubMedGoogle Scholar
- 14.Layfield LJ, Baloch ZW, Esebua M, Kannuswamy R, Schmidt RL. Impact of the reclassification of the non-invasive follicular variant of papillary carcinoma as benign on the malignancy risk of the Bethesda system for reporting thyroid cytopathology: a meta-analysis study. Acta Cytol. 2017;61(3):187–93.CrossRefPubMedGoogle Scholar
- 18.Jing X, Michael CW. The Bethesda system for reporting thyroid cytopathology: current status and future directions. J Basic Clin Med. 2015;4:52–64.Google Scholar