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Salivary Gland, Thyroid, and Parathyroid Neoplasms: Molecular Features

  • M. John Hicks
Chapter
Part of the Molecular Pathology Library book series (MPLB)

Abstract

Tumors involving the salivary, thyroid, and parathyroid glands in the pediatric age group range from benign tumors, to indeterminant malignant potential tumors to frankly malignant tumors. In addition, certain tumors may be associated with hereditary syndromes. During the past several decades, cytogenetics and molecular genetics have provided certain tumor-defining features. With the advent of rapid sequencing techniques, further definition of these tumors and identification of molecular targets for diagnosis, prognosis, and treatment have been identified. This chapter reviews the molecular features of salivary, thyroid, and parathyroid gland tumors.

Keywords

Tumors Salivary gland Thyroid Parathyroid Molecular genetics Mutations MicroRNA DNA, RNA Translocation Rearrangement Epidemiology Pediatric 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Pathology and ImmunologyTexas Children’s Hospital and Baylor College of MedicineHoustonUSA
  2. 2.Department of Pediatrics, Division of Hematology and OncologyTexas Children’s Hospital and Baylor College of MedicineHoustonUSA
  3. 3.Department of Pediatric DentistrySchool of Dentistry, University of Texas Health Science Center at HoustonHoustonUSA

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