Colitis pp 155-167 | Cite as

Treatment-Related Conditions

  • Louis LibbrechtEmail author
  • Maria Leo
  • Karel Geboes


A variety of conditions may develop as an adverse event or within the context of certain types of treatment such as endoscopic and surgical procedures, radio- and chemotherapy, and stem cell or solid organ transplantation. While the histopathological aspect of a colon biopsy or resection may suggest the diagnosis, clinical information is extremely useful because other diseases may mimic treatment-related patterns or the lesions secondary to the treatment may not be specific. This chapter overviews the morphological features and differential diagnosis of these conditions and diseases arising in the setting of certain types of treatment, excluding treatments with non-chemotherapeutic medications/drugs, which are discussed elsewhere in this book.


Radiation-induced colitis, acute Radiation-induced colitis, chronic Diversion colitis Graft-versus-host disease (GVHD) Cord colitis Hematopoietic stem cell transplantation Apoptosis Solid organ transplantation Mycophenolate Bacterial infections Viral infections Cytomegalovirus Chemotherapy-related colitis Iatrogenic injury 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of PathologyCliniques Universitaires St Luc, UCLBrusselsBelgium
  2. 2.Department of Pathology, University Hospital San Giovanni di DioUniversity of CagliariCagliariItaly
  3. 3.Department of Surgical Sciences, University Hospital San Giovanni di DioUniversity of CagliariCagliariItaly
  4. 4.Department of PathologyGhent University HospitalGhentBelgium
  5. 5.Department of PathologyKU LeuvenLeuvenBelgium

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