Pathology of Advanced Gastric Cardiac Carcinoma Cancer

  • Qin Huang


Once invading the muscularis propria and beyond, gastric cardiac carcinoma becomes much more aggressive with extensive locoregional invasion and distant metastasis. Unlike distal esophageal Barrett’s adenocarcinoma with pure tubular/papillary growth patterns, advanced gastric cardiac carcinoma demonstrates a much broader histopathologic spectrum with a substantial proportion of cases showing uncommon histologic types and rare entities, which is also more common than gastric non-cardiac carcinoma, suggesting different pathogenesis mechanisms.


Stomach Cancer Gastric cancer Gastroesophageal carcinoma Carcinoma with lymphoid stroma Poorly cohesive carcinoma Adenosquamous carcinoma 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Qin Huang
    • 1
    • 2
  1. 1.Pathology and Laboratory MedicineVeterans Affairs Boston Healthcare SystemWest RoxburyUSA
  2. 2.Harvard Medical School and Brigham and Women’s HospitalBostonUSA

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