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Pathology of Early Gastric Cardiac Cancer

  • Qin Huang
Chapter

Abstract

Early gastric cardiac cancer occurs primarily in elderly populations, frequently as protruding lesions at upper endoscopy. Microscopically, well-moderately differentiated tubular and papillary adenocarcinomas are most common in this cancer but show a variety of growth patterns, which should be distinguished from reparative/reactive changes. The risk of nodal metastasis in early gastric cardiac carcinoma is significantly lower than that in distal gastric non-cardiac carcinoma, even for intramucosal poorly cohesive/signet-ring cell carcinoma. Because of considerable fibromuscular hyperplasia in the gastric cardia, distinction between invasion of early gastric cardiac carcinoma into the muscularis mucosae and invasion into the muscularis propria is critical because of different therapeutic management strategies.

Keywords

Early gastric carcinoma Gastric cardiac carcinoma Stomach Cancer Lymph node metastasis 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Qin Huang
    • 1
    • 2
  1. 1.Pathology and Laboratory MedicineVeterans Affairs Boston Healthcare SystemWest RoxburyUSA
  2. 2.Harvard Medical School and Brigham and Women’s HospitalBostonUSA

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