Surgery in Hyperthyroidism: Toxic Adenoma and/or Multinodular Goiter
Toxic multinodular goiter is observed in areas of endemic iodine deficiency and commonly in elderly individuals. Diagnosis and assessment are made easily by physical examination, serum thyroid function tests, ultrasonography, and scintigraphy. The disease presents with subclinical hyperthyroidism in a significant part of the patients. Radioactive iodine therapy and surgery are two basic treatment methods of the disease with specific advantages and disadvantages. Selection of the treatment method is made upon factors about the disease, patient, and physician. This paper presents a case with toxic nodular goiter and discusses treatment options.
KeywordsHyperthyroidism Toxic multinodular goiter Toxic adenoma Surgery Thyroidectomy
- 1.Bülow Pedersen I, Knudsen N, Jørgensen T, Perrild H, Ovesen L, Laurberg P. Large differences in incidences of overt hyper- and hypothyroidism associated with a small difference in iodine intake: a prospective comparative register-based population survey. J Clin Endocrinol Metab. 2002;87:4462–9.CrossRefGoogle Scholar
- 16.Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid. 2016;26:1–133.CrossRefGoogle Scholar