Pathogenesis, Histopathology, and Classification

  • Salvador Pastor-Idoate
  • Salvatore Di Lauro
  • José Carlos López
  • José Carlos Pastor


Proliferative vitreoretinopathy, or PVR, is a term adopted in 1983 for describing a complication occurring after some retinal detachments (RD) [1]. PVR develops in 5–10% of RD, and although it can occur spontaneously, before surgery, it is commonest after it [2]. Pathogenesis, in the original description, was focused on the formation of membranes in both surfaces of the retina, but more recently, the existence of intraretinal changes have been added as the more severe form of PVR [3].


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Salvador Pastor-Idoate
    • 1
    • 2
  • Salvatore Di Lauro
    • 1
    • 2
  • José Carlos López
    • 1
    • 3
  • José Carlos Pastor
    • 1
    • 2
  1. 1.IOBA (Eye Institute) Retina GroupUniversity of ValladolidValladolidSpain
  2. 2.Department of OphthalmologyHospital Clinico UniversitarioValladolidSpain
  3. 3.Department of PathologyHospital Clinico UniversitarioValladolidSpain

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