The Modifiable Scaffold for Tissue Engineering

  • Kieran L. HudsonEmail author
Part of the Springer Theses book series (Springer Theses)


The scaffold chosen for investigating the application of carbohydrate-based modifiers for tissue engineering was the hSAF system previously developed in the Woolfson lab (Sect.  1.4.2) (Banwell et al., Nat Mater 8:596–600, 2009, [1]). Hydrogels are made by mixing two synthetic peptides, hSAF-p1 and hSAF-p2 (Table 4.1), that form heterodimeric coiled coils (Fig.  1.13). These heterodimers have a designed slipped interface, leading to longitudinal assembly into fibres that entangle to form the gel (Fig.  1.12).


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of ChemistryUniversity of British ColumbiaVancouverCanada

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