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Suspension Anti-Streptolysin-O (ASO/ASL) Test

  • Rowa Yousef Alhabbab
Chapter
Part of the Techniques in Life Science and Biomedicine for the Non-Expert book series (TLSBNE)

Abstract

Group A streptococcus can cause several diseases that range from mild pharyngitis and impetigo to severe post-streptococcal sequelae. Group A streptococcus produces super-antigens such as streptolysin O (SLO). Group A streptococcus can activate the immune system to produce antibodies specific to SLO. Therefore, clinical laboratories confirm previous and existing group A streptococcus infections by detecting SLO-specific antibodies in patient’s serum. Here, the principle, applications, reagents, steps, and results interpretation process of the most commonly used test in clinical laboratories to detect SLO antibodies are explored.

Keywords

GAS Streptococcus pyogenes Super-antigens Streptolysin O Anti-streptolysin O Latex agglutination 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Rowa Yousef Alhabbab
    • 1
  1. 1.Division of Applied Medical Sciences and Infectious Disease UnitKing Fahad Centre for Medical Research, King Abdulaziz UniversityJeddahSaudi Arabia

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