Precipitation and Agglutination Reactions

  • Rowa Yousef Alhabbab
Part of the Techniques in Life Science and Biomedicine for the Non-Expert book series (TLSBNE)


The interaction of antibodies and antigens leads to the formation of immune complexes that are wieldy used in serology to detect antigens or antibodies of interest in a specific manner. There are several serological methods for detecting immune complexes; however, in this chapter, only precipitation, agglutination and hemagglutination are described.


Precipitation Ring precipitation Gel diffusion Single diffusion Double diffusion Agglutination Direct agglutination Indirect agglutination Hemagglutination Direct hemagglutination Indirect hemagglutination 


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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Rowa Yousef Alhabbab
    • 1
  1. 1.Division of Applied Medical Sciences and Infectious Disease UnitKing Fahad Centre for Medical Research, King Abdulaziz UniversityJeddahSaudi Arabia

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