Precipitation and Agglutination Reactions
The interaction of antibodies and antigens leads to the formation of immune complexes that are wieldy used in serology to detect antigens or antibodies of interest in a specific manner. There are several serological methods for detecting immune complexes; however, in this chapter, only precipitation, agglutination and hemagglutination are described.
KeywordsPrecipitation Ring precipitation Gel diffusion Single diffusion Double diffusion Agglutination Direct agglutination Indirect agglutination Hemagglutination Direct hemagglutination Indirect hemagglutination
- 1.Mak TW, Saunders ME. The immune response: basic and clinical principles. Amsterdam; Boston, MA: Elsevier/Academic; 2006. p. xx. 1194.Google Scholar
- 2.Coico R, Sunshine G. Immunology: a short course. 7th ed. Chichester, West Sussex; Hoboken, NJ: John Wiley & Sons Inc.; 2015.Google Scholar
- 5.Mohan A, Saxena HM, Malhotra P. A comparison of titers of anti-Brucella antibodies of naturally infected and healthy vaccinated cattle by standard tube agglutination test, microtiter plate agglutination test, indirect hemagglutination assay, and indirect enzyme-linked immunosorbent assay. Vet World. 2016;9(7):717–22.CrossRefPubMedPubMedCentralGoogle Scholar