Atopic Dermatitis Pertaining to Adolescents
Atopic dermatitis (AD) is a chronic, relapsing, and pruritic disease that classically develops in early childhood and can persist into adulthood. There appear to be many contributing factors in the development of this disease including both genetic and environmental interactions, which ultimately lead to impaired epidermal barrier function and immune dysregulation. AD has a variable presentation depending on age, and the diagnosis is based on clinical history and diagnostic characteristics. As AD patients transition to adulthood, they are faced with a unique set of problems that need to be considered. In this chapter we will discuss management of AD in the adolescent and review specific pitfalls that may occur.
KeywordsAtopic dermatitis Eczema Pruritus Adolescence Topical corticosteroids Topical calcineurin inhibitors Antihistamines Immunosuppressants Dupilumab
- 8.Eichenfield LF, Tom WL, Berger TG, Krol A, Paller AS, Schwarzenberger K, et al. Guidelines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies. J Am Acad Dermatol. 2014;71(1):116–32.CrossRefPubMedPubMedCentralGoogle Scholar
- 19.Blauvelt A, de Bruin-Weller M, Gooderham M, Cather JC, Weisman J, Pariser D, et al. Long-term management of moderate-to-severe atopic dermatitis with dupilumab and concomitant topical corticosteroids (LIBERTY AD CHRONOS): a 1-year, randomised, double-blinded, placebo-controlled, phase 3 trial. Lancet. 2017;389(10086):2287–303.CrossRefPubMedGoogle Scholar
- 21.Nieuwlaat R, Wilczynski N, Navarro T, Hobson N, Jeffery R, Keepanasseril A, et al. Interventions for enhancing medication adherence. Cochrane Database Syst Rev. 2014;11:CD000011.Google Scholar
- 22.Sidbury R, Tom WL, Bergman JN, Cooper KD, Silverman RA, Berger TG, et al. Guidelines of care for the management of atopic dermatitis: section 4. Prevention of disease flares and use of adjunctive therapies and approaches. J Am Acad Dermatol. 2014;71(6):1218–33.CrossRefPubMedPubMedCentralGoogle Scholar