The Rh blood group system is comprised of several antigens. Because of its immunogenicity, the RhD antigen is typically matched for every patient requiring transfusion. In an emergent situation where the patient’s Rh type is unknown, it is ideal to provide RhD negative red cells and platelets. This may not be possible, especially for platelets due to their short shelf life and the relatively low incidence of RhD negative individuals in the population. If an RhD positive platelet is transfused to an RhD negative woman, prevention of sensitization to RhD may be accomplished by the administration of Rh immune globulin.
KeywordsRhD blood group Rh immune globulin Platelet transfusion
- 2.AABB, editor. Standards for blood banks and transfusion services. 31st ed. Bethesda, MD: AABB Press; 2016.Google Scholar