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Reptilia: Cellular Immunity in Reptiles: Perspective on Elements of Evolution

  • Soma Mondal Ghorai
  • Manisha Priyam
Chapter

Abstract

To understand the evolution of the immune system and its related genes, studies on reptiles are essential because they occupy a key phylogenetic position as a sister group to both birds and mammals. Reptiles comprise diverse groups presenting vast differences in morphology, reproductive, and developmental characteristics among its clades. They form the link between anamniotic amphibians and amniotic birds and are the first terrestrial animals to encounter full-blown land pathogens. Though much is known on the innate immunity of reptiles, the cellular components and cell-mediated immunity are largely unknown. Thus, the study of cellular immunity in nonavian reptiles will fill an important gap in reconstructing the evolutionary history of amniote vertebrates, which to date has been poorly represented. This chapter aims to annotate the missing links in reptilian immunology.

Keywords

Reptiles Ontogeny B lymphocytes T lymphocytes NK cells Major histocompatibility complex genes Genomics Transcriptomics Cellular immunity Evolution 

Notes

Acknowledgments

This chapter was inspired by Edwin L. Cooper, PhD, ScD, highly distinguished professor, Laboratory of Comparative Immunology, Department of Neurobiology, David Geffen School of Medicine, UCLA, and founding editor in chief of DCI (1977), eCAM (2004), and JECM (2009). I am highly indebted to him for his faith in our potential for contributing a chapter on cellular immunity in reptiles.

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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Hindu College, University of DelhiDelhiIndia
  2. 2.Department of ZoologyUniversity of DelhiDelhiIndia

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