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Digestive System

  • Abdelhamid H. Elgazzar
  • Ismet Sarikaya
Chapter

Abstract

Salivary gland scintigraphy is primarily used to assess functional impairment of salivary glands as well as to evaluate salivary duct patency and characterize salivary gland masses.

References

  1. 1.
    MacDonald A, Burrell S (2009) Infrequently performed studies in nuclear medicine: part 2. J Nucl Med Technol 37:1–13CrossRefPubMedGoogle Scholar
  2. 2.
    Wilson MA (1998) Clinical protocols. In: Wilson MA (ed) Textbook of nuclear medicine. Lippincott-Raven, Philadelphia, PA, pp 571–572Google Scholar
  3. 3.
    Mishkin ES (1981) Radionuclide salivary gland imaging. Semin Nucl Med 11:258–265CrossRefPubMedGoogle Scholar
  4. 4.
    Gates GA (1977) Sialography and scanning of the salivary glands. Otolaryngol Clin N Am 10:379–390Google Scholar
  5. 5.
    Heyman S, Respondek M (1989) Detection of pulmonary aspiration in children by radionuclide “salivagram”. J Nucl Med 30:697–699PubMedGoogle Scholar
  6. 6.
    Silver KH, Van Nostrand D (1992) Scintigraphic detection of salivary aspiration: description of a new diagnostic technique and case reports. Dysphagia 7:45–49CrossRefPubMedGoogle Scholar
  7. 7.
    Baikie G, South MJ, Reddihough DS, Cook DJ, Cameron DJ et al (2005) Agreement of aspiration tests using barium videofluoroscopy, salivagram and milk scan in children with cerebral palsy. Dev Med Child Neurol 47:86–93CrossRefPubMedGoogle Scholar
  8. 8.
    Somasundaram VH, Subramanyam P, Palaniswamy S (2012) Salivagram revisited: justifying its routine use for the evaluation of persistent/recurrent lower respiratory tract infections in developmentally normal children. Ann Nucl Med 26:578–585CrossRefPubMedGoogle Scholar
  9. 9.
    Parkman HP, Miller MA, Fisher RS (1995) Role of nuclear medicine in evaluating patients with suspected gastrointestinal motility disorders. Semin Nucl Med 25:289–305CrossRefPubMedGoogle Scholar
  10. 10.
    ACR–SNM–SPR practice guideline for the performance of gastrointestinal scintigraphy. 2010Google Scholar
  11. 11.
    Elgazzar AH (2014) Digestive System. In: Elgazzar AH (ed) Synopsis of pathophysiology in Nuclear Medicine. Springer, p 202CrossRefGoogle Scholar
  12. 12.
    ACR–SNM–SPR practice guideline for the performance of gastrointestinal scintigraphy. Revised 2010Google Scholar
  13. 13.
    Parkman HP, Maurer AH, Caroline DF, Miller DL, Krevsky B et al (1996) Optimal evaluation of patients with nonobstructive esophageal dysphagia. Manometry, scintigraphy, or videoesophagography? Dig Dis Sci 41:1355–1368CrossRefPubMedGoogle Scholar
  14. 14.
    Donohoe KJ, Maurer AH, Ziessman HA, Urbain JL, Royal HD et al (2009) Procedure guideline for adult solid-meal gastric-emptying study 3.0. J Nucl Med Technol 37:196–200CrossRefPubMedGoogle Scholar
  15. 15.
    Guo JP, Maurer AH, Urbain JL, Parkman HP (2001) Extending gastric emptying scintigraphy from two to four hours detects more patients with gastroparesis. Dig Dis Sci 46:24–29CrossRefPubMedGoogle Scholar
  16. 16.
    Ziessman HA, Bonta DV, Goetze S, Ravich WJ (2007) Experience with a new simplified and standardized four-hour gastric emptying protocol. J Nucl Med 48:568–572CrossRefPubMedGoogle Scholar
  17. 17.
    Abell TL, Camilleri M, Donohoe K, Hasler WL, Lin HC et al (2008) Consensus recommendations for gastric emptying scintigraphy: a joint report of the American Neurogastroenterology and Motility Society and the Society of Nuclear Medicine. J Nucl Med Technol 36:44–54CrossRefPubMedGoogle Scholar
  18. 18.
    Chaudhuri TK, Fink S (1991) Gastric emptying in human disease states. Am J Gastroenterol 86:533–538PubMedGoogle Scholar
  19. 19.
    Ziessman HA, Chander A, Clarke JO, Ramos A, Wahl RL (2009) The added diagnostic value of liquid gastric emptying compared with solid emptying alone. J Nucl Med 50:726–731CrossRefPubMedGoogle Scholar
  20. 20.
    Maurer AH, Camilleri M, Donohoe K, Knight LC, Madsen JL et al (2013) The SNMMI and EANM practice guideline for small-bowel and colon transit 1.0. J Nucl Med 54:2004–2013CrossRefPubMedGoogle Scholar
  21. 21.
    Maurer AH, Krevsky B (1995) Whole-gut transit scintigraphy in the evaluation of small-bowel and colon transit disorders. Semin Nucl Med 25:326–338CrossRefPubMedGoogle Scholar
  22. 22.
    Bonapace ES, Maurer AH, Davidoff S, Krevsky B et al (2000) Whole gut transit scintigraphy in the clinical evaluation of patients with upper and lower gastrointestinal symptoms. Am J Gastroenterol 95:2838–2847CrossRefPubMedGoogle Scholar
  23. 23.
    Szasz IJ, Morrison RT, Lyster DM (1985) Technetium-99m-labelled red blood cell scanning to diagnose occult gastrointestinal bleeding. Can J Surg 28:512–514PubMedGoogle Scholar
  24. 24.
    Spottswood SE, Pfluger T, Bartold SP, Brandon D, Burchell N et al (2014) SNMMI and EANM practice guideline for Meckel diverticulum scintigraphy 2.0. J Nucl Med Technol 42:163–169CrossRefPubMedGoogle Scholar
  25. 25.
    Ford PV, Bartold SP, Fink-Bennett DM, Jolles PR, Lull RJ et al (1999) Procedure guideline for gastrointestinal bleeding and Meckel’s diverticulum scintigraphy. Society of Nuclear Medicine. J Nucl Med 40:1226–1232PubMedGoogle Scholar
  26. 26.
    Smith R, Copely DJ, Bolen FH (1987) 99mTc RBC scintigraphy: correlation of gastrointestinal bleeding rates with scintigraphic findings. AJR 148:869–874CrossRefPubMedGoogle Scholar
  27. 27.
    Kostamo KL (1996) Evaluation of gastrointestinal bleeding by nuclear medicine techniques. In: Henkin RE, Bles MA, Dillehay GL, Halama JR, Karesh SM, Wagner PH, Zimmer AM (eds) Textbook of nuclear medicine. Mosby, New York, pp 1016–1022Google Scholar
  28. 28.
    Dam HQ, Brandon DC, Grantham VV, Hilson AJ, Howarth DM et al (2014) The SNMMI procedure standard/EANM practice guideline for gastrointestinal bleeding scintigraphy 2.0. J Nucl Med Technol 42:308–317CrossRefPubMedGoogle Scholar
  29. 29.
    Wang ZG, Zhang GX, Hao SH, Zhang WW, Zhang T et al (2015) Technological value of SPECT/CT fusion imaging for the diagnosis of lower gastrointestinal bleeding. Genet Mol Res 14:14947–14955CrossRefPubMedGoogle Scholar
  30. 30.
    Stebner FC, Eyler WR, DuSault LA, Block MA (1968) Identification of Warthin’s tumors by scanning of salivary glands. Am J Surg 116:513–517CrossRefPubMedGoogle Scholar
  31. 31.
    Miyake H, Matsumoto A, Hori Y, Takeoka H, Kiyosue H et al (2001) Warthin’s tumor of parotid gland on Tc-99m pertechnetate scintigraphy with lemon juice stimulation: Tc-99m uptake, size, and pathologic correlation. Eur Radiol 11:2472–2478CrossRefPubMedGoogle Scholar
  32. 32.
    Sakai E, Yoda T, Shimamoto H, Hirano Y, Kusama M et al (2003) Pathologic and imaging findings of an oncocytoma in the deep lobe of the left parotid gland. Int J Oral Maxillofac Surg 32:563–565CrossRefPubMedGoogle Scholar
  33. 33.
    Hermans P, Hausler R, Vischer TL (1977) Differential diagnosis between Gougerot-Sjögren syndrome and sialadenosis using quantitative scintigraphy of the salivary glands. Rev Rhum Mal Osteoartic 44:99–103PubMedGoogle Scholar
  34. 34.
    Madan K, Ahuja V, Gupta SD, Bal C, Kapoor A et al (2005) Impact of 24-h esophageal pH monitoring on the diagnosis of gastroesophageal reflux disease: defining the gold standard. J Gastroenterol Hepatol 20:30–37CrossRefPubMedGoogle Scholar
  35. 35.
    Shay SS, Johnson LF, Richter JE (2003) Acid reflux: a review, emphasizing detection by impedance, manometry, and scintigraphy, and the impact on acid clearing pathophysiology as well as interpreting the pH record. Dig Dis Sci 48:1–9CrossRefPubMedGoogle Scholar
  36. 36.
    Maurer AH, Parkman HP (2006) Update on gastrointestinal scintigraphy. Semin Nucl Med 36:110–118CrossRefPubMedGoogle Scholar
  37. 37.
    Levin K, Colon A, DiPalma J, Fitzpatrick S (1993) Using the radionuclide salivagram to detect pulmonary aspiration and esophageal dysmotility. Clin Nucl Med 18:110–114CrossRefPubMedGoogle Scholar
  38. 38.
    Urbain JL, Vekemans MC, Bouillon R, Van Cauteren J, Bex M et al (1993) Characterization of gastric antral motility disturbances in diabetes using a scintigraphic technique. J Nucl Med 34:576–581PubMedGoogle Scholar
  39. 39.
    Ziessman HA, Fahey FH, Collen MJ (1992) Biphasic solid and liquid gastric emptying in normal controls and diabetics using continuous acquisition in LAO view. Dig Dis Sci 37:744–750CrossRefPubMedGoogle Scholar
  40. 40.
    Couturier O, Bodet-Milin C, Querellou S, Carlier T, Turzo A (2004) Gastric scintigraphy with a liquid-solid radiolabelled meal: performances of solid and liquid parameters. Nucl Med Commun 25:1143–1150CrossRefPubMedGoogle Scholar
  41. 41.
    Kalima T, Matikainen M, Taavitsainen M (1981) The detection of duodenogastric reflux with a non-invasive method using cholescintigraphy. Scand J Gastroenterol Suppl 67:37–41PubMedGoogle Scholar
  42. 42.
    Arroyo AJ, Burns JB, Huyghe WA, Dollman AE, Patel YP (1999) Enterogastric reflux mimicking gallbladder disease: detection, quantitation and potential significance. J Nucl Med Technol 27:207–214PubMedGoogle Scholar
  43. 43.
    Middleton GW, Williams JH (1994) Significant gastric reflux of technetium-99m-MIBI in SPECT myocardial imaging. J Nucl Med 35:619–620PubMedGoogle Scholar
  44. 44.
    Howarth DM, Tang K, Lees W (2002) The clinical utility of nuclear medicine imaging for the detection of occult gastrointestinal haemorrhage. Nucl Med Commun 23:591–594CrossRefPubMedGoogle Scholar
  45. 45.
    The SNMMI Procedure Standard/EANM Practice Guideline for Gastrointestinal Bleeding Scintigraphy 2.0. 2014Google Scholar
  46. 46.
    Bentley BS, Tulchinsky M (2014) SPECT/CT helps in localization and guiding management of small bowel gastrointestinal hemorrhage. Clin Nucl Med 39:94–96CrossRefPubMedGoogle Scholar
  47. 47.
    Siddiqui AR, Schauwecker DS, Wellman HN, Mock BH (1985) Comparison of technetium-99m sulfur colloid and in vitro labeled technetium-99m RBCs in the detection of gastrointestinal bleeding. Clin Nucl Med 10:546–549CrossRefPubMedGoogle Scholar
  48. 48.
    Bunker SR, Lull RJ, Tanasescu DE, Redwine MD, Rigby J et al (1984) Scintigraphy of gastrointestinal hemorrhage: superiority of Tc-99m red blood cells over Tc-99m sulfur colloid. AJR 143:543–548CrossRefPubMedGoogle Scholar
  49. 49.
    Sfakianakis GN, Conway JJ (1981) Detection of ectopic gastric mucosa in Meckel’s 569 diverticulum and in other aberrations by scintigraphy: II. Indications and methods—a 570 10-year experience. J Nucl Med 22:732–738PubMedGoogle Scholar
  50. 50.
    Sinha CK, Pallewatte A, Easty M, De Coppi P, Pierro A et al (2013) Meckel’s scan in children: a review of 183 cases referred to two paediatric surgery specialist centres over 18 years. Pediatr Surg Int 29:511–517CrossRefPubMedGoogle Scholar
  51. 51.
    SNMMI and EANM Practice Guideline for Meckel’s Diverticulum 19 Scintigraphy V2.0, 2013Google Scholar
  52. 52.
    Sfakianakis GN, Haase GM (1982) Abdominal scintigraphy for ectopic gastric mucosa: a 612 retrospective analysis of 143 studies. AJR 138:7–12CrossRefPubMedGoogle Scholar
  53. 53.
    Chaudhuri TK, Chaudhuri TK, Christis JH (1972) False positive Meckel’s scan. Surgery 71:313PubMedGoogle Scholar
  54. 54.
    Priebe CJ, Marsden DS, Lazarevic B (1974) The use of Tc99m-pertechnetate to detect 624 transplanted gastric mucosa in the dog. J Pediatr Surg 9:605–612CrossRefPubMedGoogle Scholar
  55. 55.
    Dillman JR, Wong KK, Brown RK, Frey KA, Strouse PJ (2009) Utility of SPECT/CT with Meckel’s scintigraphy. Ann Nucl Med 23:813–815CrossRefPubMedGoogle Scholar
  56. 56.
    Hughes DK (2003) Nuclear medicine and infection detection: the relative effectiveness of imaging with 111In-oxine-, 99mTc-HMPAO-, and 99mTc-stannous fluoride colloid-labeled leukocytes and with 67Ga-citrate. J Nucl Med Technol 31:196–201PubMedPubMedCentralGoogle Scholar
  57. 57.
    Giaffer MH (1996) Labelled leucocyte scintigraphy in inflammatory bowel disease: clinical applications. Gut 38:1–5CrossRefPubMedPubMedCentralGoogle Scholar
  58. 58.
    Caobelli F, Panarotto MB, Andreoli F, Ravelli A, De Agostini A et al (2011) Is 99mTc-HMPAO granulocyte scan an alternative to endoscopy in pediatric chronic inflammatory bowel disease (IBD)? Eur J Pediatr 170:51–57CrossRefPubMedGoogle Scholar
  59. 59.
    Arndt JW, van der Sluys Veer A, Blok D, Griffoen G, Verspaget HW et al (1993) Prospective comparative study of technetium-99m-WBCs and indium-111-granulocytes for the examination of patients with inflammatory bowel disease. J Nucl Med 34:1052–1057PubMedGoogle Scholar
  60. 60.
    Society of Nuclear Medicine Procedure Guideline for Tc-99m Exametazime (HMPAO) Labeled Leukocyte Scintigraphy for Suspected Infection/Inflammation. version 2.0, approved February 7, 1999Google Scholar
  61. 61.
    Bennink RJ, Peeters M, Rutgeerts P, Mortelmans L (2004) Evaluation of early treatment response and predicting the need for colectomy in active ulcerative colitis with 99mTc-HMPAO white blood cell scintigraphy. J Nucl Med 45:1698–1704PubMedGoogle Scholar
  62. 62.
    Löffler M, Weckesser M, Franzius C, Schober O, Zimmer KP (2006) High diagnostic value of 18F-FDG-PET in pediatric patients with chronic inflammatory bowel disease. Ann N Y Acad Sci 1072:379–385CrossRefPubMedGoogle Scholar
  63. 63.
    Kerry JE, Marshall C, Griffiths PA, James MW, Scott BB (2005) Comparison between Tc-HMPAO labelled white cells and TcLeukoScan in the investigation of inflammatory bowel disease. Nucl Med Commun 26:245–251CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Abdelhamid H. Elgazzar
    • 1
  • Ismet Sarikaya
    • 1
  1. 1.Department of Nuclear MedicineKuwait UniversitySafatKuwait

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