The oxygen window first was described by Momsen, Behnke, Thalmann, Van Liew and Sass in the mid-twentieth century. They picked up the already described phenomenon of the undersaturation of blood compared to air at ambient pressure by Krogh at the beginning of the twentieth century. Behnke originally described the oxygen window as the difference between arterial and venous oxygen pressure with its 60 mmHg . Kot described the extended oxygen window (EOW) in 2015 . Additionally to the gas tension difference of oxygen and carbon dioxide, he included the total carbon dioxide and water vapour to the oxygen window. In his concept, water vapour was included as it doesn’t participate in the development of gas bubbles, even if it joins the contents of gas bubbles as a consequence of temperature. As carbon dioxide is highly reactive and doesn’t contribute to bubble formation, he added it to the EOW as well. His estimated EOW was approximately 150 mmHg, which is close to the oxygen partial pressure of the air at ambient pressure (not to be confused with alveolar air).
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