Right Heart Pathology pp 381-389 | Cite as
Myocardial Infarction of the Right Ventricle
Abstract
Right ventricular (RV) myocardial infarction (MI) usually occurs in the setting of an inferior MI (IMI) when the acute occlusion of the right coronary artery (RCA) is located proximally to the acute RV marginal branches, which commonly provide blood supply to the RV. RV MI may result in severe right heart failure with hemodynamic compromise and cardiogenic shock which distinctly differs from the cardiogenic shock secondary to left ventricular (LV) dysfunction, presenting with the clinical triad of low-output hypotension, clear lungs, and jugular venous distention despite intact global LV systolic function. The ECG provides further confirmation by examining the right precordial leads, V1 and more specifically V4R displaying ST elevation. Management of this type of cardiogenic shock is also grossly different from the management of LV shock requiring fluid resuscitation and/or vasopressors as the most important initial approach; however more definitive treatment is similar to any type of acute MI with prompt mechanical reperfusion therapy, most effectively achieved via primary percutaneous coronary intervention (PCI) of the culprit coronary artery occlusion.
Keywords
Myocardial infarction Right ventricle Coronary angiography Percutaneous coronary intervention Hypotension Cardiogenic shockAbbreviations
- AF
Atrial fibrillation
- IMI
Inferior wall myocardial infarction
- LV
Left ventric-le(-ular)
- MI
Myocardial infarction
- PCI
Percutaneous coronary intervention
- RA
Right atrium
- RCA
Right coronary artery
- RV
Right ventric-le(-ular)
- STEMI
ST elevation myocardial infarction
Notes
Conflicts of Interest
None declared.
References
- 1.Goldstein JA. Acute right ventricular infarction: insights for the interventional era. Curr Probl Cardiol. 2012;37:533–57.CrossRefPubMedGoogle Scholar
- 2.Cohn JN, Guiha NH, Broder MI, et al. Right ventricular infarction. Clinical and hemodynamic features. Am J Cardiol. 1974;33:209–14.CrossRefPubMedGoogle Scholar
- 3.Kinch JW, Ryan TJ. Right ventricular infarction. N Engl J Med. 1994;330:1211–7.CrossRefPubMedGoogle Scholar
- 4.Haji SA, Movahed A. Right ventricular infarction–diagnosis and treatment. Clin Cardiol. 2000;23:473–82.CrossRefPubMedGoogle Scholar
- 5.Goldstein JA. Pathophysiology and management of right heart ischemia. J Am Coll Cardiol. 2002;40:841–53.CrossRefPubMedPubMedCentralGoogle Scholar
- 6.Obradovic S, Dzudovic B, Djuric I, et al. Women have right ventricular infarction more frequently than men. Acta Cardiol. 2015;70:343–9.CrossRefPubMedGoogle Scholar
- 7.Dell’Italia LJ. Anatomy and physiology of the right ventricle. Cardiol Clin. 2012;30:167–87.CrossRefPubMedPubMedCentralGoogle Scholar
- 8.Haupt HM, Hutchins GM, Moore GW. Right ventricular infarction: role of the moderator band artery in determining infarct size. Circulation. 1983;67:1268–72.CrossRefPubMedGoogle Scholar
- 9.Harnett DT, LaHaye SA, Wilkinson JS. Isolated right ventricular myocardial infarction: a sheep in wolf's clothing. JAMA Intern Med. 2016;176:1207–10.CrossRefPubMedGoogle Scholar
- 10.Kanovsky J, Kala P, Novotny T, et al. Association of the right ventricle impairment with electrocardiographic localization and related artery in patients with ST-elevation myocardial infarction. J Electrocardiol. 2016;49:907–10.CrossRefPubMedGoogle Scholar
- 11.Pourafkari L, Joudi S, Ghaffari S, et al. ST-segment elevation in the right precordial leads in patients with acute anterior myocardial infarction. Balkan Med J. 2016;33:58–63.CrossRefPubMedPubMedCentralGoogle Scholar
- 12.Nourian S, Hosseinsabet A, Jalali A, et al. Evaluation of right atrial function by two-dimensional speckle-tracking echocardiography in patients with right ventricular myocardial infarction. Int J Cardiovasc Imaging. 2017;33:47–56.CrossRefPubMedGoogle Scholar
- 13.Lopez-Sendon J, Coma-Canella I, Alcasena S, et al. Electrocardiographic findings in acute right ventricular infarction: sensitivity and specificity of electrocardiographic alterations in right precordial leads V4R, V3R, V1, V2, and V3. J Am Coll Cardiol. 1985;6:1273–9.CrossRefPubMedGoogle Scholar
- 14.Finn AV, Antman EM. Images in clinical medicine. Isolated right ventricular infarction. N Engl J Med. 2003;349:1636.CrossRefPubMedPubMedCentralGoogle Scholar
- 15.Franco JJ, Brown M, Bashir R, et al. Acute anterior ST-elevation myocardial infarction and electrical storm secondary to nondominant right coronary artery occlusion. Tex Heart Inst J. 2014;41:335–7.CrossRefPubMedPubMedCentralGoogle Scholar
- 16.Peters A, Lakhter V, Bashir R. Under-pressure: right ventricular infarction. Am J Med. 2015;128:966–9.CrossRefPubMedPubMedCentralGoogle Scholar
- 17.Tomala M, Miszalski-Jamka T, Zajdel W, et al. Angiographic result of index PCI determines the presence of right ventricular infarction in patients with acute inferior myocardial infarction. Int J Cardiovasc Imaging. 2015;31:1591–601.CrossRefPubMedPubMedCentralGoogle Scholar
- 18.Fiol M, Cygankiewicz I, Carrillo A, et al. Value of electrocardiographic algorithm based on “ups and downs” of ST in assessment of a culprit artery in evolving inferior wall acute myocardial infarction. Am J Cardiol. 2004;94:709–14.CrossRefPubMedPubMedCentralGoogle Scholar
- 19.Garcia-Niebla J, Fiol M, Carrillo-Lopez A, et al. Electrocardiographic diagnosis of right ventricular infarction by proximal occlusion of a very dominant right coronary artery. Am J Med. 2016;129:e41–2.CrossRefPubMedPubMedCentralGoogle Scholar
- 20.Lu ML, De Venecia T, Patnaik S, et al. Atrial myocardial infarction: a tale of the forgotten chamber. Int J Cardiol. 2016;202:904–9.CrossRefPubMedGoogle Scholar
- 21.Chiladakis JA, Patsouras N, Manolis AS. The Bezold-Jarisch reflex in acute inferior myocardial infarction: clinical and sympathovagal spectral correlates. Clin Cardiol. 2003;26:323–8.CrossRefPubMedGoogle Scholar
- 22.Harjola VP, Mebazaa A, Celutkiene J, et al. Contemporary management of acute right ventricular failure: a statement from the heart failure association and the working group on pulmonary circulation and right ventricular function of the european society of cardiology. Eur J Heart Fail. 2016;18:226–41.CrossRefPubMedPubMedCentralGoogle Scholar
- 23.Ondrus T, Kanovsky J, Novotny T, et al. Right ventricular myocardial infarction: from pathophysiology to prognosis. Exp Clin Cardiol. 2013;18:27–30.PubMedPubMedCentralGoogle Scholar
- 24.Mattioli AV, Bastia E, Mattioli G. Doppler echocardiographic findings in patients with right ventricular infarction. J Ultrasound Med. 1998;17:297–301.CrossRefPubMedGoogle Scholar
- 25.Fairbairn TA, Motwani M, Greenwood JP, et al. CMR for the diagnosis of right heart disease. JACC Cardiovasc Imaging. 2012;5:227–9.CrossRefPubMedGoogle Scholar
- 26.Grothoff M, Elpert C, Hoffmann J, et al. Right ventricular injury in ST-elevation myocardial infarction: risk stratification by visualization of wall motion, edema, and delayed-enhancement cardiac magnetic resonance. Circ Cardiovasc Imaging. 2012;5:60–8.CrossRefPubMedGoogle Scholar
- 27.Inohara T, Kohsaka S, Fukuda K, et al. The challenges in the management of right ventricular infarction. Eur Heart J Acute Cardiovasc Care. 2013;2:226–34.CrossRefPubMedPubMedCentralGoogle Scholar
- 28.Gopalakrishnan A, Sanjay G, Nair KK, et al. Deleterious effects of isolated right ventricular pacing in right ventricular myocardial infarction. Int J Cardiol. 2016;222:995–6.CrossRefPubMedGoogle Scholar
- 29.Manolis A, Varriale P, Nobile J. Low filling pressure cardiogenic pulmonary-edema–a complication of venodilatory therapy. N Y State J Med. 1986;86:411–3.PubMedGoogle Scholar
- 30.Gorter TM, Lexis CP, Hummel YM, et al. Right ventricular function after acute myocardial infarction treated with primary percutaneous coronary intervention (from the glycometabolic intervention as adjunct to primary percutaneous coronary intervention in ST-segment elevation myocardial infarction III trial). Am J Cardiol. 2016;118:338–44.CrossRefPubMedGoogle Scholar
- 31.Aissaoui N, Sorbets E, Sleiman C, et al. Characteristics, mortality and prognostic factors of acute right ventricular myocardial infarction: a case-control study. Ann Cardiol Angeiol (Paris). 2017;66:15–20.CrossRefGoogle Scholar
- 32.Jacobs AK, Leopold JA, Bates E, et al. Cardiogenic shock caused by right ventricular infarction: a report from the SHOCK registry. J Am Coll Cardiol. 2003;41:1273–9.CrossRefPubMedPubMedCentralGoogle Scholar
- 33.Goldstein JA, Kommuri N, Dixon SR. Left ventricular systolic dysfunction is associated with adverse outcomes in acute right ventricular infarction. Coron Artery Dis. 2016;27:277–86.CrossRefPubMedGoogle Scholar
- 34.Smarz K, Zaborska B, Jaxa-Chamiec T, et al. Right ventricular systolic function as a marker of prognosis after ST-elevation inferior myocardial infarction 5-year follow-up. Int J Cardiol. 2016;221:549–53.CrossRefPubMedGoogle Scholar