Hydroxyapatite: Design with Nature

  • Xiao YangEmail author


Hydroxyapatite, the basic inorganic material in bone, has been used widely in orthopaedic applications. In this chapter, we report the recent advances in research regarding hydroxyapatite. Biomineralization process as well as synthesis routes of hydroxyapatite is discussed. This chapter also addresses several new features of hydroxyapatite material discovered when co-culturing with different cells. Its traditional as well as the potential future applications are found at the end of the chapter.


Biomineralization Intracellular calcium Bone Hydroxyapatite nanoparticles Crystallite growth Bioceramic Hybrid structure Osteogenic differentiation Tumor cell apoptosis Selective effect Orthopedic implant Drug delivery 



The author wishes to thank Professor Xingdong Zhang (National Engineering Research Center for Biomaterials, Sichuan University) for providing insightful comments to this manuscript. The author is grateful to Professor Kai Zhang and Xiangdong Zhu from our research center for their technical guidance.


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2017

Authors and Affiliations

  1. 1.National Engineering Research Center for BiomaterialsSichuan UniversityChengduChina

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