Central Centrifugal Cicatricial Alopecia

  • Pooya Khan Mohammad Beigi


Central centrifugal cicatricial alopecia (CCCA) is an umbrella term created by the North American Hair Research Society (NAHRS), which broadly includes previous terms of “hot comb alopecia,” “follicular degeneration syndrome,” “pseudopelade” in African Americans, and “central elliptical pseudopelade” in Caucasians [4]. CCCA is the most common form of permanent hair loss in African American females and is a type of primary inflammatory cicatricial alopecia.


Central centrifugal cicatricial alopecia (CCCA) Hot comb alopecia Follicular degeneration syndrome Pseudopelade Dermal collagen Hasten disease Centrifugal pattern Dermal collagen Brad hyalinized fibrous tract Premature desquamation Elastic sheath Granulomatous inflammation Lichen planopilaris Frontal fibrosing alopecia Folliculitis decalvans Discoid lupus erythematosus Traction alopecia Topical anti-inflammatory agent Topical corticosteroid Tacrolimus Pimecrolimus Tetracyclines Intralesional Injections Triamcinolone Acetonide Immunomodulatory Minoxidil 


  1. 1.
    Whiting DA, Olsen EA. Central centrifugal cicatricial alopecia. Dermatol Ther. 2008;21(4):268–78. Scholar
  2. 2.
    Herskovitz I, Miteva M. Central centrifugal cicatricial alopecia: challenges and solutions. Clin Cosmet Investig Dermatol. 2016;9:175–81. Retrieved Apr 30, 2017, from Scholar
  3. 3.
    Khumalo NP, Gumedze F. Traction: risk factor or coincidence in central centrifugal cicatricial alopecia? Br J Dermatol. 2012;167:1191–3. Scholar
  4. 4.
    Blattner C, Polley DC, Ferritto F, Elston DM. Central centrifugal cicatricial alopecia. Indian Dermatol Online J. 2013;4(1):50–1. Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Pooya Khan Mohammad Beigi
    • 1
    • 2
    • 3
  1. 1.Department of Health ManagementNew York Medical CollegeValhallaUSA
  2. 2.University of British ColumbiaVancouverCanada
  3. 3.Misdiagnosis AssociationSeattleUSA

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