Analgesia, Sedation, and Delirium in the ICU

  • Douglas R. Oyler
  • Andrew C. BernardEmail author


Pain, agitation, and delirium in the ICU are common occurrences; and inappropriate management of these conditions is clearly associated with poorer outcomes, including increased length of mechanical ventilation, length of ICU stay, and risk of mortality. Within this chapter we discuss the best practices regarding both assessment and treatment of these conditions as well as the pharmacology of available agents for analgesia, sedation, and delirium management. A comprehensive approach to improving patient care and comfort is also proposed.


Sedation Analgesia Delirium Opioids Benzodiazepines 



All authors report no conflicts of interest, including pharmaceutical or industry support, regarding any of the information contained in this report. No relevant funding from any organization was provided to any of the authors regarding this manuscript or the ideas contained herein.


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of PharmacyUniversity of Kentucky Chandler Medical CenterLexingtonUSA
  2. 2.Department of SurgeryUniversity of KentuckyLexingtonUSA

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