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In-Stent Restenosis

  • Roisin Colleran
  • Robert A. Byrne
Chapter

Abstract

Restenosis is an arterial wall healing response to mechanical injury at the site of a previously treated coronary segment. In-stent restenosis (ISR) is an angiographic diagnosis, defined as recurrent diameter stenosis >50% within a stent or at its edges (5 mm segments proximal and distal to the stent). It is the most common cause of stent failure and the most common reason for target lesion revascularization (TLR). Moreover, its treatment is challenging owing to a relatively high rate of recurrence at follow-up.

Keywords

In-stent restenosis Drug-coated balloon Drug-eluting stent Bare metal stent Neointimal hyperplasia Neoatherosclerosis Scoring balloon Cutting balloon 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Deutsches Herzzentrum München, Technische Universität MünchenMunichGermany
  2. 2.DZHK (German Centre for Cardiovascular Research), partner site Munich Heart AllianceMunichGermany

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