Coronary Artery Disease: Assessing Regional Wall Motion

  • Paramjit Jeetley
  • Rajdeep S. Khattar
  • Roxy Senior


The assessment of left ventricular systolic function and particularly regional wall motion has become increasingly important in determining the severity and prognosis of coronary artery disease (CAD). Echocardiography, with its high spatial and temporal resolution, is an ideally suited non-invasive method of assessing such changes in wall motion. In the acute situation, the ability to detect these changes can be very useful in the early detection of myocardial ischemia, even preceding ECG changes and symptoms. Equally in patients presenting acutely with chest pain, with inconclusive ECGs, normal regional wall motion may help to exclude underlying myocardial ischaemia.


Coronary artery disease Regional wall motion abnormalities Contrast 3D Strain 


  1. 1.
    Senior R, Basu S, Khattar R, Lahiri A. Independent prognostic value of the extent and severity of systolic wall thickening abnormality at infarct site after thrombolytic therapy. Am Heart J. 1998;135:1093–8.CrossRefGoogle Scholar
  2. 2.
    Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, Pennell DJ, Rumberger JA, Ryan T, Verani MS. Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart: a statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Circulation. 2002;105:539–42.CrossRefGoogle Scholar
  3. 3.
    Kober L, Torp-Pederson C, Carlsen J, Videbaeck R, Egelblad H. An echocardiographic method for selecting high risk patients shortly after acute myocardial infarction for inclusion in multicentre studies (as used in TRACE study) TRAndalopril Cardiac Evaluation. Eur Heart J. 1994;15:1616–20.CrossRefGoogle Scholar
  4. 4.
    Kjoller E, Kober L, Jorgenson S, Torp-Penderson C. Long term prosgnostic importance of hyperkinesia following acute myocardial infarction. TRACE study group. TRAndalopril Cardiac Evaluation. Am J Cardiol. 1999;83:655–9.CrossRefGoogle Scholar
  5. 5.
    Leibermann AN, Weiss JL, Jugdutt BI, et al. Two-dimensional echocardiography and infarct size:relationship of regional wall motion and thickening to the extent of myocardialinfarction in the dog. Circulation. 1981;63:739–46.CrossRefGoogle Scholar
  6. 6.
    Swinburn JM, Stubbs P, Soman P, Collinson P, Lahiri A, Senior R. Independent value of tissue harmonic echocardiography for risk stratification in patients with non-ST-segment elevation acute chest pain. J Am Soc Echocardiogr. 2002;15:1031–7.CrossRefGoogle Scholar
  7. 7.
    Platts DG, Monaghan MJ. Colour encoded endocardial tracking:the current state of play. Eur J Echocardiogr. 2003;4:6–16.CrossRefGoogle Scholar
  8. 8.
    Mor-Avi V, Sugeng L, Lang RM. Real time 3-dimensional echocardiography: an integral component of the echocardiographic examination in adult patients? Circulation. 2009;119:314–29.CrossRefGoogle Scholar
  9. 9.
    Ozkan A, et al. Assessment of left ventricular function in aortic stenosis. Nat Rev Cardiol. 2011;8:494–501.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Paramjit Jeetley
    • 1
  • Rajdeep S. Khattar
    • 2
  • Roxy Senior
    • 2
  1. 1.Department of Cardiovascular MedicineNorthwick Park Hospital and Institute for Medical ResearchMiddlesexUK
  2. 2.Royal Brompton Hospital and Imperial CollegeLondonUK

Personalised recommendations