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Microfluidic Systems

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Cardiac Cell Culture Technologies

Abstract

Microfluidic technology has a great application potential in many fields of science such as analytical chemistry, molecular biology, or biotechnology. The microfluidic systems are also widely used for cell engineering. The microsystems have several advantages comparing with the traditional analysis, such as: using small volumes of reagents, low power consumption, flexibility, and adaptability to different experimental conditions and purposes. Additionally, in vivo conditions can be better mimicked in the microsystems than in conventional culture methods. In this chapter, the microfluidic systems for cellular application are described. We present important parameters of the microdevices, which have the greatest impact on the cell behavior. The advantages and disadvantages of using the microfluidic systems are also extensively discussed. Furthermore, we characterize some cellular models (static and perfusion; monolayer and spatial) developed in the microsystems. This chapter is an overview of basics of the microfluidic systems for cellular application.

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Acknowledgements

This work was realized with the frame of project SONATA 5 program No. UMO-2013/09/D/ST5/03887.

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Authors and Affiliations

  1. The Chair of Medical Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Warsaw, Poland

    Sandra Skorupska, Elzbieta Jastrzebska, Michal Chudy, Artur Dybko & Zbigniew Brzozka

Authors
  1. Sandra Skorupska
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  2. Elzbieta Jastrzebska
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  3. Michal Chudy
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  4. Artur Dybko
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  5. Zbigniew Brzozka
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Corresponding author

Correspondence to Sandra Skorupska .

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Editors and Affiliations

  1. The Chair of Medical Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Warsaw, Poland

    Zbigniew Brzozka

  2. The Chair of Medical Biotechnology, Faculty of Chemistry, Warsaw University of Technology, Warsaw, Poland

    Elzbieta Jastrzebska

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Skorupska, S., Jastrzebska, E., Chudy, M., Dybko, A., Brzozka, Z. (2018). Microfluidic Systems. In: Brzozka, Z., Jastrzebska, E. (eds) Cardiac Cell Culture Technologies. Springer, Cham. https://doi.org/10.1007/978-3-319-70685-6_2

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  • DOI: https://doi.org/10.1007/978-3-319-70685-6_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-70684-9

  • Online ISBN: 978-3-319-70685-6

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