The Child with Chronic Liver Disease

  • Deirdre KellyEmail author


The main causes of chronic liver disease in children are: neonatal liver disease (see Chap.  1); alpha-1-anti-trypsin deficiency (see Chap.  1); autoimmune liver disease (see Chap.  6); cystic fibrosis (see Chap.  8), chronic viral hepatitis, non-alcoholic fatty liver disease liver disease (NAFLD) and metabolic liver disease (see Chaps.  1 and  2) (Table 7.1).

Further Reading

  1. Angeli P, Sanyal A, Moller S, et al. Current limits and future challenges in the management of renal dysfunction in patients with cirrhosis: report from the International Club of Ascites. Liver Int. 2013;33:16–23.CrossRefPubMedGoogle Scholar
  2. Ebel N, Horslen S. Complications and management of chronic liver disease. In: Kelly DA, editor. Diseases of the liver and biliary system in children. 4th ed. New York, NY: Wiley; 2017. p. 343–68.Google Scholar
  3. Nobili V, Alkhouri N, Alisi A. Nonalcoholic fatty liver disease: a challenge for pediatricians. JAMA Pediatrics. 2015;169:170–6.CrossRefPubMedGoogle Scholar
  4. Shneider BL, Bosch J, de Franchis R, et al. Portal hypertension in children: expert pediatric opinion on the report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension. Pediatr Transplant. 2012;16:426–37.CrossRefPubMedGoogle Scholar
  5. Vilstrup H, Amodio P, Bajaj J, et al. Hepatic encephalopathy in chronic liver disease: 2014 practice guideline by the American Association for the Study of Liver Diseases and the European Association for the Study of the Liver. Hepatology. 2014;60:715–35.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.The Liver UnitBirmingham Women’s and Children’s HospitalBirminghamUK

Personalised recommendations