Intestinal Transplantation

  • Khalid SharifEmail author


The incidence of Intestinal Failure (IF) in children is estimated to be 1–2 per million population. In children, the causes of IF are: short bowel syndrome, disorders of bowel motility and primary mucosal disease (Table 12.1). The indications for Intestinal transplantation (ITX) in children are irreversible intestinal failure (IF) associated with complications such as: loss of central venous access or life threatening line sepsis. A combined liver/intestine transplant is indicated if the child has developed intestinal failure associated liver disease (IFALD). Children should be considered for intestinal transplant assessment before they develop irreversible multi-organ failure.

Further Reading

  1. de Ville MA, Mayer AD, Beath SV, McKiernan PJ, Kelly DA. En block combined reduced-liver and small bowel transplants: from large donors to small children. Transplantation. 2000;69:555–9.CrossRefGoogle Scholar
  2. Gupte G, Mazeriegos G. Small bowel transplantation. In: Kelly DA, editor. Diseases of the liver and biliary system in children. 4th ed. Chichester: Wiley; 2017. p. 538–55.CrossRefGoogle Scholar
  3. Kato T, Tzakis A, Selvaggi G, Madariaga J. Surgical techniques used in intestinal transplantation. Curr Opin Organ Transplant. 2004;9:207–13.CrossRefGoogle Scholar
  4. Mazariegos GV, Soltys K, Bond G, et al. Pediatric intestinal retransplantation: techniques, management, and outcomes. Transplantation. 2008;86:1777–82.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.The Liver UnitBirmingham Women’s and Children’s HospitalBirminghamUK

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