Hidradenitis suppurativa (HS) or acne inversa is a chronic, inflammatory, recurrent, debilitating skin disease of the hair follicles that usually presents after puberty with painful, deep-seated, inflamed lesions in the apocrine gland-bearing areas of the body, most commonly the axillae, inguinal, and anogenital regions . The disease affects mainly young adults with a female predominance (female to male ratio 2.4–3.3:1). Among the various populations and skin types, prevalence and incidence often differ, but there are no differences in major clinical characteristics. Spontaneous resolution of the disease is rare. Medical treatment targets the inflammatory response, and surgical intervention reduces the burden of the disease offering an overall better outcome. In addition, lifestyle modifications like smoking cessation and weight loss play an important role in improving the prognosis of HS. In recent studies, patients with hidradenitis suppurativa, blistering diseases, leg ulcers, psoriasis, and eczemas had the highest risk for reduction of health-related quality of life among all other non-tumor dermatological conditions .
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