CT and CT Colonography
Computed tomography (CT) can identify with accuracy locally advanced colon cancer and liver metastases, but it cannot diagnose peritoneal carcinomatosis. CT can identify T3/T4 tumors with more than 5 mm extramural depth which are candidates for neoadjuvant therapy. Screening with CT colonography shows similar detection rates of advanced neoplasia with those of colonoscopy. Patients with polyps ≥10 mm in size or three or more polyps 6–9 mm in size should be referred for colonoscopy. If the initial CT colonography is negative for cancer or polyps ≥6 mm, follow-up in 5 years with CT colonography is recommended. Increased adherence to population-based CT colonography screening is feasible due to technological advances in multidetector row CT scanners and computer-aided detection software in addition to stool-tagging low-preparation techniques.
- 5.Regge D, Laudi C, Galatola G, Della Monica P, Bonelli L, Angelelli G, Asnaghi R, Barbaro B, Bartolozzi C, Bielen D, Boni L, Borghi C, Bruzzi P, Cassinis MC, Galia M, Gallo TM, Grasso A, Hassan C, Laghi A, Martina MC, Neri E, Senore C, Simonetti G, Venturini S, Gandini G (2009) Diagnostic accuracy of computed tomographic colonography for the detection of advanced neoplasia in individuals at increase risk of colorectal cancer. JAMA 301:2453–2461CrossRefGoogle Scholar
- 10.Berrington de González A, Kim KP, Knudsen AB, Lansdorp-Vogelaar I, Rutter CM, Smith-Bindman R, Yee J, Kuntz KM, van Ballegooijen M, Zauber AG, Berg CD (2011) Radiation-related cancer risks from CT colonography screening: a risk-benefit analysis. AJR Am J Roentgenol 196(4):816–823CrossRefGoogle Scholar
- 13.Levin B, Lieberman DA, McFarland B, Smith RA, Brooks D, Andrews KS, Dash C, Giardiello FM, Glick S, Levin TR, Pickhardt P, Rex DK, Thorson A, Winawer SJ, American Cancer Society Colorectal Cancer Advisory Group; US Multi-Society Task Force; American College of Radiology Colon Cancer Committee (2008) Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. CA Cancer J Clin 58(3):130–160CrossRefGoogle Scholar