Comparative View of Lung Vascular Endothelium of Cattle, Horses, and Water Buffalo

Chapter
First Online:
Part of the Advances in Anatomy, Embryology and Cell Biology book series (ADVSANAT, volume 228)

Abstract

Endothelium plays an important role in maintaining the vascular barrier and physiological homeostasis. Endothelium also is fundamental to the initiation and regulation of inflammation. Endothelium demonstrates phenotypic and functional heterogeneity not only among various organs but also within an organ. One of the striking examples would be the pulmonary endothelium that participates in creating blood–air barrier. Endothelium in large pulmonary blood vessels is distinct in structure and function from that lining of the pulmonary capillaries. This chapter focuses on the comparative aspects of pulmonary endothelium and highlight unique differences such as the presence of pulmonary intravascular macrophages among select species.

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  • David Schneberger
    • 1
  • Ram S. Sethi
    • 2
  • Baljit Singh
    • 3
  1. 1.Canadian Centre for Health and Safety in AgricultureUniversity of SaskatchewanSaskatoonCanada
  2. 2.School of Animal BiotechnologyGuru Angad Dev Veterinary and Animal Sciences UniversityLudhianaIndia
  3. 3.Faculty of Veterinary MedicineUniversity of CalgaryCalgaryCanada

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