Advertisement

Patient-Reported Outcomes in Sexual Medicine

  • Stanley E. Althof
Chapter
Part of the Trends in Andrology and Sexual Medicine book series (TASM)

Abstract

This chapter reviews the most relevant male and female sexuality patient-reported outcomes (PROs) and discusses the process of psychometric validation. The constructs of reliability, various forms of validity, sensitivity, and specificity as well as concerns with translating a PRO into a different language are discussed.

Two tables, one for male PROs and one for female PROs, delineate both multidimensional assessment measures and questionnaires for evaluation of specific sexual dysfunctions. Additionally, both tables include quality of life measures and sexuality measures that can be employed with specific populations.

PROs are valuable tools in the assessment of sexual function in both research and clinical settings. They serve as a useful adjunct to identify and detect treatment benefits and quality of life concerns in individuals with sexual problems.

References

  1. 1.
    American Psychiatric Association. The diagnostic and statistical manual of mental disorders. 5th ed. Washington, DC: American Psychiatric Association; 2013.CrossRefGoogle Scholar
  2. 2.
    Rosen RC, Riley A, Wagner G, Osterloh IH, Kirkpatrick J, Mishra A. The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction. Urology. 1997;49(6):822–30.CrossRefPubMedGoogle Scholar
  3. 3.
    Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA. Oral sildenafil in the treatment of erectile dysfunction. Sildenafil Study Group. N Engl J Med. 1998;338(20):1397–404.  https://doi.org/10.1056/NEJM199805143382001.CrossRefPubMedGoogle Scholar
  4. 4.
    Rosen R, Brown C, Heiman J, Leiblum S, Meston C, Shabsigh R, et al. The Female Sexual Function Index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther. 2000;26(2):191–208.CrossRefGoogle Scholar
  5. 5.
    Derogatis L, Clayton A, Lewis-D’Agostino D, Wunderlich G, Fu Y. Validation of the female sexual distress scale-revised for assessing distress in women with hypoactive sexual desire disorder. J Sex Med. 2008;5(2):357–64.  https://doi.org/10.1111/j.1743-6109.2007.00672.x.CrossRefPubMedGoogle Scholar
  6. 6.
    Rosen RC, Catania J, Pollack L, Althof S, O’Leary M, Seftel AD. Male Sexual Health Questionnaire (MSHQ): scale development and psychometric validation. Urology. 2004;64(4):777–82.  https://doi.org/10.1016/j.urology.2004.04.056.CrossRefPubMedGoogle Scholar
  7. 7.
    Hellstrom W, Feldman R, Rosen R, Smith T, Kaufman G, Tursi J. Bother and distress associated with Peyronie’s disease: validation of the Peyronie’s disease questionnaire. J Urol. 2013;190(2):627–34.CrossRefPubMedGoogle Scholar
  8. 8.
    Althof S. Patient reported outcomes in the assessment of premature ejaculation. Transl Androl Urol. 2016;5(4):470–4.Google Scholar
  9. 9.
    Gravetter F, Forzano L. Research methods for the behavioral sciences. 4th ed. Belmont: Wadsworth; 2012.Google Scholar
  10. 10.
    Holden R. Face validity. In: Weiner I, Craighead E, editors. The corsini encyclopedia of psychology. 4th ed. New Jersey: Wiley; 2010. p. 637–8.Google Scholar
  11. 11.
    Hatzichristou D, Kirana P, Banner L, Althof S, Lonnee-Hoffmann R, Dennerstein L, et al. Diagnosing sexual dysfunction in men and women: sexual history taking and the role of symptom scales and questionnaires. J Sex Med. 2016;13:1166–82.CrossRefPubMedGoogle Scholar
  12. 12.
    Wild D, Grove A, Martin M, Eremenco S, McElroy S, Verjee-Lorenz A, et al. Principles of good practice for the translation and cultural adaptation process for Patient-Reported Outcomes (PRO) measures: report of the ISPOR Task Force for Translation and Cultural Adaptation. Value Health. 2005;8(2):94–104.CrossRefPubMedGoogle Scholar
  13. 13.
    McGahuey C, Gelenberg A, Laukes C, Moreno R, Delgado P, McKnight K, et al. The Arizona Sexual Experience Scale (ASEX): reliability and validity. J Sex Marital Ther. 2000;26:25–40.CrossRefPubMedGoogle Scholar
  14. 14.
    Mulhall J, Goldstein I, Bushmakin A, Cappelleri J, Hvidsten K. Validation of the erection hardness score. J Sex Med. 2007;4:1626–34.CrossRefPubMedGoogle Scholar
  15. 15.
    Rosen RC, Catania J, Althof S, Pollack L, O’Leary M, Seftel AD, et al. Development and validaton of four-item version of male sexual health questionnaire to assess ejaculatory dysfunction. Urology. 2007;69:805–9.CrossRefPubMedGoogle Scholar
  16. 16.
    Patrick DL, Giuliano F, Ho KF, Gagnon DD, McNulty P, Rothman M. The premature ejaculation profile: validation of self-reported outcome measures for research and practice. BJU Int. 2009;103(3):358–64.  https://doi.org/10.1111/j.1464-410X.2008.08041.x.CrossRefPubMedGoogle Scholar
  17. 17.
    Althof S, Rosen R, Symonds T, Mundayat R, May K, Abraham L. Development and validation of a new questionnaire to assess sexual satisfaction, control, and distress associated with premature ejaculation. J Sex Med. 2006;3(3):465–75.  https://doi.org/10.1111/j.1743-6109.2006.00239.x.CrossRefPubMedGoogle Scholar
  18. 18.
    Symonds T, Perelman M, Althof S, Giuliano F, Martin M, May K, et al. Development and validation of a premature ejaculation diagnostic tool. Eur Urol. 2007;52:565–73.CrossRefPubMedGoogle Scholar
  19. 19.
    Althof S, Corty E, Levine S. EDITS: development of a quesitonnaire for evaluating satisfaction with treatment for erectile dysfunction. Urology. 1999;53:793–9.CrossRefPubMedGoogle Scholar
  20. 20.
    DiBenedetti DB, Gondek K, Sagnier PP, Kubin M, Marquis P, Keininger D, et al. The treatment satisfaction scale: a multidimensional instrument for the assessment of treatment satisfaction for erectile dysfunction patients and their partners. Eur Urol. 2005;48(3):503–11.  https://doi.org/10.1016/j.eururo.2005.05.008.CrossRefPubMedGoogle Scholar
  21. 21.
    Althof S, Cappelleri JC, Shpilsky A. Treatment responsiveness of the self-esteem and relationship questionnaire in erectile dysfunction. Urology. 2003;61:888–92.CrossRefPubMedGoogle Scholar
  22. 22.
    Abraham L, Symonds T, Morris MF. Psychometric validation of a sexual quality of life questionnaire for use in men with premature ejaculation or erectile dysfunction. J Sex Med. 2008;5(3):595–601.  https://doi.org/10.1111/j.1743-6109.2007.00749.x.CrossRefPubMedGoogle Scholar
  23. 23.
    Flynn K, Lin L, Cyranowski M. Development of the NIH PROMIS (R) sexual function and satisfaction measures in patients with cancer. J Sex Med. 2013;10(7):43–52.CrossRefPubMedPubMedCentralGoogle Scholar
  24. 24.
    Quirk F, Haughie S, Symonds T. The use of the sexual function questionnaire as a screening tool for women with sexual dysfunction. J Sex Med. 2005;2(4):469–77.  https://doi.org/10.1111/j.1743-6109.2005.00076.x.CrossRefPubMedGoogle Scholar
  25. 25.
    Clayton AH, Segraves RT, Leiblum S, Basson R, Pyke R, Cotton D, et al. Reliability and validity of the Sexual Interest and Desire Inventory-Female (SIDI-F), a scale designed to measure severity of female hypoactive sexual desire disorder. J Sex Marital Ther. 2006;32(2):115–35.  https://doi.org/10.1080/00926230500442300.CrossRefPubMedGoogle Scholar
  26. 26.
    Melzack R. The McGill pain questionnaire: major properties and scoring methods. Pain. 1975;1:277–99.CrossRefPubMedGoogle Scholar
  27. 27.
    McCoy N. The McCoy female sexuality questionnaire. Qual Life Res. 2000;9:739–45.CrossRefGoogle Scholar
  28. 28.
    Symonds T, Boolell M, Quirk F. Development of a questionnaire on sexual quality of life in women. J Sex Marital Ther. 2005;31(5):385–97.  https://doi.org/10.1080/00926230591006502.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Case Western Reserve University School of MedicineClevelandUSA
  2. 2.Center for Marital and Sexual Health of South FloridaWest Palm BeachUSA

Personalised recommendations