Negative-Pressure Wound Therapy

  • Lauren R. BayerEmail author


Negative-pressure wound therapy has become an accepted therapy for many types of acute and chronic wounds including deep pressure injuries, vascular ulcers, traumatic wounds, postsurgical wounds, and burns. Mechanism of action includes wound contraction, microdeformational healing, granulation tissue formation, fluid evacuation, moisture balance, and microbial management. The wound-healing device can be used in many anatomic locations and for various wound types. New applications, risks, and contraindications are discussed.


Negative-pressure wound therapy NPWT Wound healing Microdeformational healing Surgical wounds Diabetic ulcers Vascular ulcers Lower extremity wounds Pressure injuries Instillation therapy 

Supplementary material

Video 12.1

Application of NPWT dressing over a debrided heel pressure ulcer after split-thickness skin grafting (AVI 345614 kb)


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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Wound Care Center, Department of Surgery, Division of Plastic SurgeryBrigham and Women’s Hospital – Harvard Medical SchoolBostonUSA

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