Hot Topics in TAVI: Paravalvular Leak, Thrombosis, PM Implantation, Stroke, Durability

  • Caterina GandolfoEmail author
  • Amerigo Stabile


Transcatheter aortic valve implantation (TAVI) is a rapidly evolving technique providing robust treatment of severe aortic valve stenosis, at least in high and intermediate risk patient cohorts [1]. However, different important limitations, having a potential impact on patient outcome, still need to be resolved. Indeed, with several first-generation balloon-expandable or self-expanding TAVI prostheses, residual paravalvular aortic regurgitation (PVL) after TAVI has been identified as a significant independent major predictor of acute and long-term mortality. Moreover, conduction disorders requiring pacemaker implantation and also concerns about early (leaflet thrombosis/decreased leaflet motion) and late valve durability, need to be resolved before applying TAVI to lower-risk patient cohorts [2].


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Authors and Affiliations

  1. 1.Mediterranean Institute for Transplantation and Advanced Specialized Therapies (ISMETT)IRCSS UPMC ITALYPalermoItaly
  2. 2.Maria Eleonora HospitalPalermoItaly

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