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Compressed Sensing on Multi-pinhole Collimator SPECT Camera for Sentinel Lymph Node Biopsy

  • Carlo SeppiEmail author
  • Uri Nahum
  • Peter A. von Niederhäusern
  • Simon Pezold
  • Michael Rissi
  • Stephan K. Haerle
  • Philippe C. Cattin
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 10434)

Abstract

State-of-the-art imaging devices for sentinel lymph node biopsy are either a 1-dimensional gamma probe or more recently 2-dimensional gamma cameras that locate the sentinel lymph node. These devices, however, share difficulties when multiple lymph nodes are close-by and do not allow the estimation of the distance to the lymph nodes, as the tracer activation is projected either to a 1- or 2-dimensional image plane. We propose a method, which reconstructs the tracer distribution using a single image of the detector resulting from a multi-pinhole collimator. Applying standard image processing tools on the detector’s image leads to a reduced, sparse system. Thus, we propose an efficient and reliable compressed sensing strategy, to reconstructs the 3-dimensional tracer distribution using a multi-pinhole collimator and a single detector image. This approach enables better estimation of lymph nodes position and improves the differentiation of close-by lymph nodes.

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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Carlo Seppi
    • 1
    Email author
  • Uri Nahum
    • 1
  • Peter A. von Niederhäusern
    • 1
  • Simon Pezold
    • 1
  • Michael Rissi
    • 2
  • Stephan K. Haerle
    • 3
  • Philippe C. Cattin
    • 1
  1. 1.Center for medical Image Analysis and Navigation (CIAN), Department of Biomedical EngineeringUniversity of BaselAllschwilSwitzerland
  2. 2.Head of Research and PhysicsDECTRIS Ltd.Baden-DaetwilSwitzerland
  3. 3.Head and Neck Surgical OncologyHirslanden Clinic St. Anna LucerneLuzernSwitzerland

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