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Nail Tumors

  • Nilton Di Chiacchio
  • Nilton Gioia Di Chiacchio
  • Leandro Fonseca Noriega
Chapter

Abstract

A wide range of tumors can affect the nail apparatus, due to its morphological complexity. Tumors of the nail apparatus may affect, primarily or secondarily, the nail matrix or nail bed, surrounding epidermis, dermis, hypodermis, blood vessels, adnexal glands and osteocartilaginous structures. Thus, a lesion of the proximal nail fold can cause secondary changes in the nail plate owing to nail matrix compression.

Nail imaging (X-ray, ultrasound, tomography, and magnetic resonance imaging) are helpful in the diagnostic investigation, but the histopathology remains as the gold standard method. Depending on the origin and aggressiveness of the lesion, different therapeutic approaches can be performed, since topical medications to Mohs micrographic surgery. In general, surgical management is the treatment of choice.

Keywords

Glomus tumor Implanted epidermoid cyst SUKA SCC Nail tumors Myxoid pseudocyst Neuromas Onychoclavus Onychomatricoma Onychopapilloma Benign eruptive hemangioma Schwannoma Subungual exostosis Subungual keratoacanthoma Superficial acral fibromyxoma Warts 

References

  1. 1.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 638–41.Google Scholar
  2. 2.
    McCown H, Thiers B, Cook J, et al. Global nail dystrophy associated with HPV type 57 infection. Br J Dermatol. 1999;141:731–5.PubMedCrossRefGoogle Scholar
  3. 3.
    Herschthal J, McLeod MP, Zaiac M. Management of ungual warts. Dermatol Ther. 2012;25:545–50.CrossRefPubMedGoogle Scholar
  4. 4.
    Shapiro L, Flushing NY, Stoller NM. Erosion of phalanges by subungual warts, report of a case. JAMA. 1961;176:379.CrossRefGoogle Scholar
  5. 5.
    Gardner LW, Acker DW. Bone destruction of a distal phalanx caused by periungual warts. Arch Dermatol. 1973;107:275–6.PubMedCrossRefGoogle Scholar
  6. 6.
    Plewig G, Christophers E, Braun-Falco O. Mutilierende subunguale Warzen: Abheilung durch Methortrexat. Hautarzt. 1973;24:338–41.PubMedGoogle Scholar
  7. 7.
    Shah SS, Kothari UR, Dhoshi HV, Bhat AC, Bhalodia GC. Erosion of phalanx by subungual wart. Indian J Dermatol Venereol Leprol. 1976;42:185–6.PubMedGoogle Scholar
  8. 8.
    Kumar B, Sharma SC, Kaur S. Phalangeal erosions with subungual warts. Indian J Dermatol Venereol Leprol. 1960;46:166–8.Google Scholar
  9. 9.
    Baumbach JL, Sheth PB. Topical and intralesional antiviral agents. In: Wolverton S, editor. Comprehensive dermatologic drug therapy, vol. 27. Philadelphia: WB Saunders Company; 2001. p. 524–36.Google Scholar
  10. 10.
    Shelley WB, Shelley ED. Intralesional bleomycin sulfate therapy for warts. A novel bifurcated needle puncture technique. Arch Dermatol. 1991;127:234–6.PubMedCrossRefGoogle Scholar
  11. 11.
    Bigby M, Gibbs S, Harvey I, Sterling J. Warts. Clin Evid. 2004;11:2209–23.Google Scholar
  12. 12.
    Olbright SM, Stern RS, Tang SV, et al. Complications of cutaneous laser surgery, a survey. Arch Dermatol. 1987;123:345–9.CrossRefGoogle Scholar
  13. 13.
    Street ML, Roenigk RK. Recalcitrant periungual verrucae: the role of carbon dioxide laser vaporization. J Am Acad Dermatol. 1990;23:115–20.PubMedCrossRefGoogle Scholar
  14. 14.
    Ross BS, Levine VJ, Nehal K, et al. Pulsed dye laser treatment for warts: an update. Dermatol Surg. 1999;25:277–380.CrossRefGoogle Scholar
  15. 15.
    Yoo KH, Kim BJ, Kim MN. Enhanced efficacy of photodynamic therapy with methyl 5-aminolevulinic acid in recalcitrant periungual warts after ablative carbon dioxide fractional laser: a pilot study. Dermatol Surg. 2009;35:1927–32.PubMedCrossRefGoogle Scholar
  16. 16.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 679–81.Google Scholar
  17. 17.
    Baran R. Retinoids and the nails. J Dermatol Treat. 1990;1:151–4.CrossRefGoogle Scholar
  18. 18.
    Bouscarat F, Bouchard C, Bachour D. Paronychia and pyogenic granuloma of the great toes in patients treated with indinavir. N Engl J Med. 1998;338:1776–7.PubMedCrossRefGoogle Scholar
  19. 19.
    Higgins EM, Hughes JR, Snowdon S, et al. Cyclosporin induced periungual granulation tissue. Br J Dermatol. 1995;132:829–30.CrossRefPubMedGoogle Scholar
  20. 20.
    Zaballos P, Carulla M, Ozdemir F, et al. Dermoscopy of pyogenic granuloma: a morphological study. Br J Dermatol. 2010;163:1229–37.PubMedCrossRefGoogle Scholar
  21. 21.
    Weedon D. Weedon’s skin pathology. 3rd ed. Churchill Livingstone Elsevier; 2010. Chapter 38, Vascular tumors; p. 906–7.Google Scholar
  22. 22.
    Wollina U, Unger L, Haroske G, Heinig B. Classification of vascular disorders in the skin and selected data on new evaluation and treatment. Dermatol Ther. 2012;25(4):287–96.PubMedCrossRefGoogle Scholar
  23. 23.
    Greenberger S, Boscolo E, Adini I, Mulliken JB, Bischoff J. Corticosteroid suppression of VEGF-A in infantile hemangioma-derived stem cells. N Engl J Med. 2010;362:1005–13.PubMedPubMedCentralCrossRefGoogle Scholar
  24. 24.
    Longhurst WD, Khachemoune A. An unknown mass: the differential diagnosis of digit tumors. Int J Dermatol. 2015;54(11):1214–25.PubMedCrossRefGoogle Scholar
  25. 25.
    Sobanko JF, Dagum AB, Davis IC, Kriegel DA. Soft tissue tumors of the hand. 1. Benign. Dermatol Surg. 2007;33(6):651–67.PubMedGoogle Scholar
  26. 26.
    Poetke M, Berlien HP. Treatment of a subungual hemangioma with flashlamp-pumped pulsed-dye laser. J Am Acad Dermatol. 2000;43(6):1135–6.PubMedCrossRefGoogle Scholar
  27. 27.
    Frieden IJ, Eichenfield LF, Esterly NB, Geronemus R, Mallory S. Guidelines of care for hemangiomas of infancy. American Academy of Dermatology Guidelines/Outcomes Committee. J Am Acad Dermatol. 1997;37:631–7.PubMedCrossRefGoogle Scholar
  28. 28.
    Piraccini BM, Antonucci A, Rech G, Iorizzo M, Neri I, Patrizi A, Tosti A. Congenital pseudoclubbing of a fingernail caused by subungual hemangioma. J Am Acad Dermatol. 2005;53(2 Suppl 1):S123–6.PubMedCrossRefGoogle Scholar
  29. 29.
    Walsh JJ 4th, Eady JL. Vascular tumors. Hand Clin. 2004;20(3):261–8.PubMedCrossRefGoogle Scholar
  30. 30.
    Baek HJ, Lee SJ, Cho KH, Choo HJ, Lee SM, Lee YH, Suh KJ, Moon TY, Cha JG, Yi JH, Kim MH, Jung SJ, Choi JH. Subungual tumors: clinicopathologic correlation with US and MR imaging findings. Radiographics. 2010;30(6):1621–36.PubMedCrossRefGoogle Scholar
  31. 31.
    Darrow DH, Greene AK, Mancini AJ, Nopper AJ. Section on dermatology, section on otolaryngology – head and neck surgery, and section on plastic surgery. Diagnosis and management of infantile hemangioma. Pediatrics. 2015;136(4):1060–104.CrossRefGoogle Scholar
  32. 32.
    Cham E, Smoller BR, Lorber DA, Victor TA, Cibull TL. Epithelioid hemangioma (angiolymphoid hyperplasia with eosinophilia) arising on the extremities. J Cutan Pathol. 2010;37(10):1045–52.CrossRefPubMedGoogle Scholar
  33. 33.
    Al-Qattan MM, Al-Rikabi AC. Epitheloid hemangioendothelioma of the subcutaneous tissues of a finger. Indian J Orthop. 2014;48(5):522–4.PubMedPubMedCentralCrossRefGoogle Scholar
  34. 34.
    Nasr E, Timbang MR, Naffaa L, Doumit GD. Epitheloid hemangioma treated with naproxen sodium. J Craniofac Surg. 2014;25(6):2059–61.PubMedCrossRefGoogle Scholar
  35. 35.
    Huang SC, Zhang L, Sung YS, Chen CL, Krausz T, Dickson BC, Kao YC, Agaram NP, Fletcher CD, Antonescu CR. Frequent FOS gene rearrangements in epithelioid hemangioma: a molecular study of 58 cases with morphologic reappraisal. Am J Surg Pathol. 2015;39(10):1313–21.PubMedPubMedCentralCrossRefGoogle Scholar
  36. 36.
    Roh J, Song MJ, Lee MW, Park CS. Solid form of epithelioid hemangioma: a case report. Korean J Pathol. 2014 Oct;48(5):394–7.PubMedPubMedCentralCrossRefGoogle Scholar
  37. 37.
    Al-Daraji WI, Prescott RJ, Abdellaoui A, Khan MM, Kulkarni K, Youssef MM, Zelger BG, Zelger B. Cutaneous epithelioid angiomatous nodule: different views or interpretations in the analysis of ten new cases. Dermatol Online J. 2009;15(3):2.PubMedGoogle Scholar
  38. 38.
    Rosai J, Gold J, Landy R. The histiocytoid hemangiomas. A unifying concept embracing several previously described entities of skin, soft tissue, large vessels, bone, and heart. Hum Pathol. 1979;10(6):707–30.PubMedCrossRefGoogle Scholar
  39. 39.
    Dannaker C, Piacquadio D, Willoughby CB, Goltz RW. Histiocytoid hemangioma: a disease spectrum. Report of a case with simultaneous cutaneous and bone involvement limited to one extremity. J Am Acad Dermatol. 1989;21(2 Pt2):404–9.PubMedCrossRefGoogle Scholar
  40. 40.
    Tosti A, Peluso AM, Fanti PA, Torresan F, Solmi L, Bassi F. Histiocytoid hemangioma with prominent fingernail involvement. Dermatology. 1994;189(1):87–9.PubMedCrossRefGoogle Scholar
  41. 41.
    Haneke E. Comment on subungual vascular malformation with unusual presentation. J Cutan Aesthet Surg. 2012;5(4):291–4.PubMedPubMedCentralGoogle Scholar
  42. 42.
    Cone RO, Hudkins P, Nguyen V, Merriwether WA. Histiocytoid hemangioma of bone: a benign lesion which may mimic angiosarcoma. Report of a case and review of literature. Skelet Radiol. 1983;10(3):165–9.CrossRefGoogle Scholar
  43. 43.
    Accardo G, Nele G, Turrà F, La Rusca I, Schonauer F. A rare case of ‘histiocytoid haemangioma’ of the hand. J Plast Reconstr Aesthet Surg. 2013;66(11):318–20.CrossRefGoogle Scholar
  44. 44.
    Rettig AC, Strickland JW. Glomus tumor of the digits. J Hand Surg. 1977;2:261–5.CrossRefGoogle Scholar
  45. 45.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 680–5.Google Scholar
  46. 46.
    Hildreth DH. The ischemia test for glomus tumor: a new diagnostic test. Rev Surg. 1970;27:147–8.PubMedGoogle Scholar
  47. 47.
    Cigna E, Carlesimo B, Bistoni G, et al. The value of clinical diagnosis of glomus tumors. Acta Chir Plast. 2008;50:55–8.PubMedGoogle Scholar
  48. 48.
    Love JG. Glomus tumors: diagnosis and treatment. Proc Mayo Clin. 1944;19:113–6.Google Scholar
  49. 49.
    Maehara Lde S, Ohe EM, Enokihara MY, Michalany NS, Yamada S, Hirata SH. Diagnosis of glomus tumor by nail bed and matrix dermoscopy. An Bras Dermatol. 2010;85:236–8.CrossRefPubMedGoogle Scholar
  50. 50.
    Van Geertruden J, Lorea P, Goldschmidt D, et al. Glomus tumours of the hand. J Hand Surg. 1996;21B(2):257–60.CrossRefGoogle Scholar
  51. 51.
    Marchadier A, Cohen M, Legre R. Subungual glomus tumors of the fingers: ultrasound diagnosis. Chir Main. 2006;25:16–21.PubMedCrossRefGoogle Scholar
  52. 52.
    Wortsman X, Jemec G. Role of high variable frequency ultrasound in the preoperative diagnosis of glomus tumors: a pilot study. Am J Clin Dermatol. 2009;10:23–7.PubMedCrossRefGoogle Scholar
  53. 53.
    Drapé J-L, Idy-Peretti S, Goettmann S, et al. Subungual glomus tumors: Evaluation with MR imaging. Radiology. 1995;195:507–15.PubMedCrossRefGoogle Scholar
  54. 54.
    Weedon D. Weedon’s skin pathology. 3rd ed. Churchill Livingstone Elsevier; 2010. Chapter 38, Vascular tumors; p. 907–8.Google Scholar
  55. 55.
    McDermott EM, Weiss AP. Glomus tumors. J Hand Surg. 2006;31A:1397–400.CrossRefGoogle Scholar
  56. 56.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 690–2.Google Scholar
  57. 57.
    De Palma L, Gigante A, Specchia N. Subungual exostosis of the foot. Foot Ankle Int. 1996;17:758–63.PubMedCrossRefGoogle Scholar
  58. 58.
    Stieler W, Reinel D, Jänner M, Haneke E. Ungewöhnliche Lokalisation einer subungualen Exostose. Akt Dermatol. 1989;15:32–4.Google Scholar
  59. 59.
    Badawy Abdel-Naser M, Zouboulis CC, Anagnostopoulos I. Subungual exostosis. Eur J Dermatol. 1992;2:345–7.Google Scholar
  60. 60.
    Davis DA, Cohen PR. Subungual exostosis. Case report and review of the literature. Pediatr Dermatol. 1996;13:212–8.PubMedCrossRefGoogle Scholar
  61. 61.
    Letts M, Davidson D, Nizalik E. Subungual exostosis: diagnosis and treatment in children. J Trauma, Injury Infect Crit Care. 1998;44:346–9.CrossRefGoogle Scholar
  62. 62.
    Baran R, Sayag J. Exostose sous-unguéale de l’index. Ann Dermatol Vénéréol. 1978;105:1075–6.PubMedGoogle Scholar
  63. 63.
    Velanovich V. Subungual pigmented lesion caused by a bone spur: a mimic of a subungual melanoma. Milit Med. 1994;159:663.CrossRefGoogle Scholar
  64. 64.
    Sebastian G. Subunguale Exostosen der Grosszehe, Berufsstigma bei Tänzern. Dermatol Monatsschr. 1977;163:998–1000.PubMedGoogle Scholar
  65. 65.
    Fikry T, Harfaoui A, Zahid M, et al. Exostose sousunguéale digitale. A propos d’un cas. Main. 1998;3:77–82.Google Scholar
  66. 66.
    Lemont H, Christman RA. Subungual exostosis and nail disease and radiologic aspects. In: Scher R, Daniel CR, editors. Nails: therapy, diagnosis, surgery. Philadelphia: W.B. Saunders; 1990. p. 250–7.Google Scholar
  67. 67.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 693–4.Google Scholar
  68. 68.
    Yanagi T, Akiyama M, Arita K, Shimizu H. Nail deformities associated with hereditary multiple exostoses. J Am Acad Dermatol. 2005;53:534–5.PubMedCrossRefGoogle Scholar
  69. 69.
    Solomon L. Chondrosarcoma in hereditary multiple exostosis. S Afr Med J. 1974;48:671–6.PubMedGoogle Scholar
  70. 70.
    Smith DW. Recognizable patterns of human malformation. Genetic, embryologic and clinical aspects. 4th ed. Philadelphia: W.B. Saunders; 1988.Google Scholar
  71. 71.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 692–3.Google Scholar
  72. 72.
    Apfelberg DB, Druker D, Maser M, et al. Subungual osteochondroma. Arch Dermatol. 1979;115:472–3.PubMedCrossRefGoogle Scholar
  73. 73.
    Dumontier CA, Abimelec P. Nail unit enchondromas and osteochondromas: a surgical approach. Dermatol Surg. 2001 Mar;27(3):274–9.PubMedGoogle Scholar
  74. 74.
    Schulze KE, Hebert AA. Diagnostic features, differential diagnosis, and treatment of subungual osteochondroma. Pediatr Dermatol. 1994;11:39–41.PubMedCrossRefGoogle Scholar
  75. 75.
    Kim SW, Moon SE, Kim JA. A case of subungual osteochondroma. J Dermatol. 1998;25:60–2.PubMedCrossRefGoogle Scholar
  76. 76.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 695.Google Scholar
  77. 77.
    Shelley WB, Ralston EL. Paronychia due to enchondroma. Arch Dermatol. 1964;90:412–3.PubMedCrossRefGoogle Scholar
  78. 78.
    Pastinszky I, Dévai J. Paronychia et onychodystrophia enchondromatosa. Börgyógyászati és Venerelogiai Szemle. 1968;44:176–8.Google Scholar
  79. 79.
    Wawrosch W, Rassner G. Monströses Enchondrom des Zeigefingerendgliedes mit Nageldeformierung. Hautarzt. 1985;36:168–9.PubMedGoogle Scholar
  80. 80.
    Yaffee HW. Peculiar nail dystrophy caused by an enchondroma. Arch Dermatol. 1965;91:361.PubMedCrossRefGoogle Scholar
  81. 81.
    Koff AB, Goldberg LH, Ambergel D. Nail dystrophy in a 35-year-old man. Arch Dermatol. 1996;132:223–8.PubMedCrossRefGoogle Scholar
  82. 82.
    Bellinghausen HW, Weeks PM, Young LV, Gilula LA. Chondrosarcoma of distal phalanx. Orthop Rev. 1983;12:97–100.Google Scholar
  83. 83.
    Nakajima H, Ushigome S, Fukuda J. Case report 482: chondrosarcoma (grade 1) arising from the right second toe in patient with multiple enchondromas. Skelet Radiol. 1988;17:289–92.CrossRefGoogle Scholar
  84. 84.
    Shimizu K, Kotoura Y, Nishijima N, Nakamura T. Enchondroma of the distal phalanx of the hand. J Bone Joint Surg. 1997;79A:898–900.CrossRefGoogle Scholar
  85. 85.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 696–7.Google Scholar
  86. 86.
    Aulicino PL, DuPuy TE, Moriarity RP. Osteoid osteoma of the terminal phalanx of finger. Orthop Rev. 1981;10:59–63.Google Scholar
  87. 87.
    Foucher G, Lemarechal P, Citron N, et al. Osteoid osteoma of the distal phalanx. A report of four cases and review of the literature. J Hand Surg. 1987;12B:382–6.CrossRefGoogle Scholar
  88. 88.
    Saville PD. A medical option for the treatment of osteoid osteoma. Arthritis Rheum. 1980;23:1409–11.PubMedCrossRefGoogle Scholar
  89. 89.
    Sullivan M. Osteoid osteoma of the fingers. Hand. 1971;3:175–8.PubMedCrossRefGoogle Scholar
  90. 90.
    Lindbom A, Lindvall N, Sodenberg G, Spujt H. Angiographyin osteoid osteoma. Acta Radiol Stockh. 1960;54:327–33.CrossRefGoogle Scholar
  91. 91.
    O’Hara JP, Tegmeyer C, Sweet DE, MacCue FC. Angiography in the diagnosis of osteoid osteoma of the hand. J Bone Joint Surg. 1975;57A:163–6.CrossRefGoogle Scholar
  92. 92.
    Braun S, Chevro A, Tomeno B, et al. Les ostéomes ostéoides phalangiens. Méd Hyg (Genève). 1980;38:1222–9.Google Scholar
  93. 93.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 703–8.Google Scholar
  94. 94.
    Li K, Barankin B. Digital mucous cysts. J Cutan Med Surg. 2010;14(5):199–206.PubMedCrossRefGoogle Scholar
  95. 95.
    Zuber TJ. Office management of digital mucous cysts. Am Fam Physician. 2001;64(12):1987–90.PubMedGoogle Scholar
  96. 96.
    Drapé JL, Idy-Peretti I, Goettmann S, et al. MR imaging of digital mucoid cysts. Radiology. 1996;200:531–6.CrossRefPubMedGoogle Scholar
  97. 97.
    Lin YC, Wu YH, Scher RK. Nail changes and association of osteoarthritis in digital myxoid cyst. Dermatol Surg. 2008;34:364–9.PubMedGoogle Scholar
  98. 98.
    Richert B, Lecerf P, Caucanas M, André J. Nail tumors. Clin Dermatol. 2013;31(5):602–17.CrossRefPubMedGoogle Scholar
  99. 99.
    De Berker DA, Lawrence CM. Treatment of myxoid cysts. Dermatol Surg. 2001;27:296–9.PubMedGoogle Scholar
  100. 100.
    de Berker D, Goettman S, Baran R. Subungual myxoid cysts: clinical manifestations and response to therapy. J Am Acad Dermatol. 2002;46:394–8.CrossRefPubMedGoogle Scholar
  101. 101.
    Weedon D. Weedon’s skin pathology. 3rd ed. Churchill Livingstone Elsevier; 2010. Chapter 13, Cutaneous mucinoses; p. 360–2.Google Scholar
  102. 102.
    Cohen PR, Scher RK. Geriatric nail disorders: diagnosis and treatment. J Am Acad Dermatol. 1992;26(4):521–31.CrossRefPubMedGoogle Scholar
  103. 103.
    Abdullah L, Abbas O. Common nail changes and disorders in older people: Diagnosis and management. Can Fam Physician. 2011;57(2):173–81.PubMedPubMedCentralGoogle Scholar
  104. 104.
    Singh D, Bentley G, Trevino SG. Callosities, corns, and calluses. BMJ. 1996;312(7043):1403–6.PubMedPubMedCentralCrossRefGoogle Scholar
  105. 105.
    Singh G, Haneef NS, Uday A. Nail changes and disorders among the elderly. Indian J Dermatol Venereol Leprol. 2005;71(6):386–92.PubMedCrossRefGoogle Scholar
  106. 106.
    Aksoy HM, Aksoy B, Balci M, Üstün H. Onychoclavus due to subungual exostosis: reconstruction of the resulting defect by triple volar advancement flap: surgical technique. Turkiye Klinikleri J Med Sci. 2011;31(2):496–9.CrossRefGoogle Scholar
  107. 107.
    de Berker DA, Wlodek C, Bristow IR. Subungual corn: a tender pigmented subungual lesion in older people. Br J Dermatol. 2014;171(1):69–72.CrossRefPubMedGoogle Scholar
  108. 108.
    Baran R. The nail in the elderly. Clin Dermatol. 2011;29(1):54–60.CrossRefPubMedGoogle Scholar
  109. 109.
    Perrin C, Cannata GE, Bossard C, Grill JM, Ambrossetti D, Michiels JF. Onychocytic matricoma presenting as pachymelanonychia longitudinal. A new entity (report of five cases). Am J Dermatopathol. 2012;34(1):54–9.CrossRefPubMedGoogle Scholar
  110. 110.
    Wanat KA, Reid E, Rubin AI. Onychocytic matricoma: a new, important nail unit tumor mistaken for a foreign body. JAMA Dermatol. 2014;150(3):335–7.PubMedCrossRefGoogle Scholar
  111. 111.
    Spaccarelli N, Wanat KA, Miller CJ, Rubin AI. Hypopigmented onychocytic matricoma as a clinical mimic of onychomatricoma: clinical, intraoperative and histopathologic correlations. J Cutan Pathol. 2013;40(6):591–4.PubMedCrossRefGoogle Scholar
  112. 112.
    Perrin C. Tumors of the nail unit. A review. Part II: acquired localized longitudinal pachyonychia and masked nail tumors. Am J Dermatopathol. 2013;35(7):693–709.CrossRefPubMedGoogle Scholar
  113. 113.
    Bon-Mardion M, Poulalhon N, Balme B, Thomas L. Ungual seborrheic keratosis. J Eur Acad Dermatol Venereol. 2010;24(9):1102–4.PubMedGoogle Scholar
  114. 114.
    Lapidoth M, Israeli H, Ben Amitai D, Halachmi S. Treatment of verrucous epidermal nevus: experience with 71 cases. Dermatology. 2013;226(4):342–6.PubMedCrossRefGoogle Scholar
  115. 115.
    Brandling-Bennett HA, Morel KD. Epidermal Nevi. Pediatr Clin N Am. 2010;57(5):1177–98.CrossRefGoogle Scholar
  116. 116.
    Kim R, Marmon S, Kaplan J, Kamino H, Pomeranz MK. Verrucous epidermal nevus. Dermatol Online J. 2013;19(12):20707.PubMedGoogle Scholar
  117. 117.
    Carbotti M, Coppola R, Graziano A, Verona Rinati M, Paolilli FL, Zanframundo S, Panasiti V. Dermoscopy of verrucous epidermal nevus: large brown circles as a novel feature for diagnosis. Int J Dermatol. 2015.  https://doi.org/10.1111/ijd.12948. [Epub ahead of print] PubMed PMID: 26475079
  118. 118.
    Dhanaraj M, Ramalingam M. Systematised epidermal nevus – a case report. J Clin Diagn Res. 2015;9(2):WD01–2.  https://doi.org/10.7860/JCDR/2015/9190.5510.CrossRefPubMedPubMedCentralGoogle Scholar
  119. 119.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4nd ed. Oxford: Blackwell Scientific; 2012. p. 649.Google Scholar
  120. 120.
    Hauber K, Rose C, Bröcker EB, Hamm H. Lichen striatus: clinical features and follow-up in 12 patients. Eur J Dermatol. 2000;10(7):536–9.PubMedGoogle Scholar
  121. 121.
    Su WP. Histopathologic varieties of epidermal nevus. A study of 160 cases. Am J Dermatopathol. 1982;4(2):161–70.PubMedCrossRefGoogle Scholar
  122. 122.
    Baran R, Klint A. Onychomatrixoma: filamentous tufted tumor in the matrix of a funnel-shaped entity (report of three cases). Br J Dermatol. 1992;126(5):510–5.PubMedCrossRefGoogle Scholar
  123. 123.
    Haneke E, Fränken J. Onychomatricoma. Dermatol Surg. 1995;21:984–7.PubMedGoogle Scholar
  124. 124.
    Duhard E, Baptiste C, Monegier du Sorbier C. Onychomatricome: deux nouveaux cas. Nouv Dermatol. 1996;15:461.Google Scholar
  125. 125.
    Perrin C, Goettmann S, Baran R. Onychomatricoma: clinical and histopathologic findings in 12 cases. J Am Acad Dermatol. 1998;39:560–4.PubMedCrossRefGoogle Scholar
  126. 126.
    Raison-Peyron N, Alirezai M, Meunier L, Barnéon G, Meynadier J. Onychomatricoma: an unusual cause of nail bleeding. Clin Exp Dermatol. 1998;23:138.PubMedCrossRefGoogle Scholar
  127. 127.
    Van Holder C, Dumontier C, Abimelec P. Onychomatricoma. J Hand Surg. 1999;24B:120–1.CrossRefGoogle Scholar
  128. 128.
    Fraga GR, Patterson JW, McHargue CA. Onychomatricoma: report of a case and its comparison with fibrokeratoma of the nail bed. Am J Dermatopathol. 2001;23:36–40.PubMedCrossRefGoogle Scholar
  129. 129.
    Juillard J, Michaud T, Schubert B. Onychomatricome. Presented at the Premier Symposium International d’Onychologie, Paris, March 24, 1994.Google Scholar
  130. 130.
    Tosti A, Piraccini BM, Calderon O, et al. Onychomatricoma: report of three cases including the first recognized in a coloured man. Eur J Dermatol. 2000;10:604–6.PubMedGoogle Scholar
  131. 131.
    Piraccini BM, Antonucci A, Rech G, Starace M, Misciali C, Tosti A. Onychomatricoma: first description in a child. Pediatr Dermatol. 2007;24(1):46–8.CrossRefPubMedGoogle Scholar
  132. 132.
    Di Chiacchio N, Tavares GT, Tosti A, Di Chiacchio NG, Di Santis E, Alvarenga L, Stuhr P, De Farias D. Onychomatricoma: epidemiological and clinical findings in a large series of 30 cases. Br J Dermatol. 2015.  https://doi.org/10.1111/bjd.13900. [Epub ahead of print] PubMed PMID: 25970230
  133. 133.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. Oxford: Blackwell Scientific Publications; 2012. p. 637–743.Google Scholar
  134. 134.
    Miteva M, de Farias DC, Zaiac M, Romanelli P, Tosti A. Nail clipping diagnosis of onychomatricoma. Arch Dermatol. 2011 Sep;147(9):1117–8.PubMedCrossRefGoogle Scholar
  135. 135.
    Soto R, Wortsman X, Corredoira Y. Onychomatricoma: clinical and sonographic findings. Arch Dermatol. 2009;145:1461–2.PubMedCrossRefGoogle Scholar
  136. 136.
    Perrin C, Baran R, Pisani A, Ortonne JP, et al. The onychomatricoma: additional histologic criteria and immunohistochemical study. Am J Dermatopathol. 2002;24:199–203.PubMedCrossRefGoogle Scholar
  137. 137.
    Goettmann S, Zaraa I, Moulonguet I. Onychomatricoma with pterygium aspect: unusual clinical presentation. Acta Derm Venereol. 2006;86(4):369–70.PubMedCrossRefGoogle Scholar
  138. 138.
    Weedon D. Weedon’s skin pathology. 3rd ed. Churchill Livingstone Elsevier; 2010. Chapter 31, Tumors of the epidermis; p. 702.Google Scholar
  139. 139.
    Di Chiacchio N, Richert B, Haneke E. Surgery of the matrix. In: Richert B, Di Chiacchio N, Haneke E, editors. Nail surgery. London: Informa Healthcare; 2010. p. 118–20.Google Scholar
  140. 140.
    Chavaillaz O, Borradoril L, Haneke E. Subungual epidermoid cyst: report of a case with rapid growth and nail loss mimicking a malignant tumor. Derma. 2010;1(2):73–5.Google Scholar
  141. 141.
    Vergles D, Horzic M, Cupurdija K, Lackovic Z, Vergles JM. Epidermoid cyst on top of the left arm thumb. Am J Dermatopathol. 2009;31(7):723–4.PubMedCrossRefGoogle Scholar
  142. 142.
    Radke S, Walther M, Ettl V, König A. Epidermoid cyst mimicking monoarticular arthritis of the great toe. Rheumatol Int. 2004;24(2):117–9.PubMedCrossRefGoogle Scholar
  143. 143.
    Baran R, Bureau H. Two post-operative epidermoid cysts following realignment of the hallux nail. Br J Dermatol. 1988;119(2):245–7.PubMedCrossRefGoogle Scholar
  144. 144.
    Molloy DO, Herbert K. Sub-ungual epidermoid cyst. J Hand Surg Br. 2006;31(3):345.PubMedCrossRefGoogle Scholar
  145. 145.
    Lee KM, Park JH, Min KH, Kim EK. Epidermal cyst on the sole. Arch Plast Surg. 2013;40(4):475–6.PubMedPubMedCentralCrossRefGoogle Scholar
  146. 146.
    Baran R, Broutart JC. Epidermoid cyst of the thumb presenting as pincer nail. J Am Acad Dermatol. 1988;19(1 Pt 1):143–4.PubMedCrossRefGoogle Scholar
  147. 147.
    Sáez-de-Ocariz MM, Domínguez-Cherit J, García-Corona C. Subungual epidermoid cysts. Int J Dermatol. 2001;40(8):524–6.PubMedCrossRefGoogle Scholar
  148. 148.
    Webb DW, Clarke A, Fryer A, Osborne JP. The cutaneous features of tuberous sclerosis: a population study. Br J Dermatol. 1996;135:1–5.PubMedCrossRefGoogle Scholar
  149. 149.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 664–7.Google Scholar
  150. 150.
    Zeller J, Friedmann D, Clerici T, Revuz J. The significance of a single periungual fibroma: report of seven cases. Arch Dermatol. 1995;131:1465–6.PubMedCrossRefGoogle Scholar
  151. 151.
    Steel HH. Garlic-clove fibroma. JAMA. 1965;191:1082–3.PubMedCrossRefGoogle Scholar
  152. 152.
    LoBuono P, Jothikumar T, Kornblee L. Acquired digital fibrokeratoma. Cutis. 1979;24:50–1.PubMedGoogle Scholar
  153. 153.
    Kikuchi I, Ishii Y, Inoue S. Acquired periungual fibroma. J Dermatol. 1978;5:235–7.PubMedCrossRefGoogle Scholar
  154. 154.
    Haneke E. Intraoperative differential diagnosis of onychomatricoma, Koenen’s tumours, and hyperplastic Bowen’s disease. J Euro Acad Dermatol Venereol. 1998b;11:S119.CrossRefGoogle Scholar
  155. 155.
    Haneke E. Multiple subungual keratoacanthomas. Presented at the XII International Congress of Dermatology Surgery, Munich, Oct 4–7, 1991. In: Zbl Haut-GeschlKr. 1991;159:337.Google Scholar
  156. 156.
    Cahn RL. Acquired periungual fibrokeratoma. Arch Dermatol. 1977;113:1564–8.PubMedCrossRefGoogle Scholar
  157. 157.
    Heller J. Die Krankheiten der Nägel. In: Jadassohn J, editor. Handbuch der Hautund Geschlechtskrankheiten. Spezielle Dermatologie. Berlin: Springer; 1927.;Bd VIII/2.Google Scholar
  158. 158.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 671.Google Scholar
  159. 159.
    Tosti A, Schneider SL, Ramirez-Quizon MN, Zaiac M, Miteva M. Clinical, dermoscopic, and pathologic features of onychopapilloma: a review of 47 cases. J Am Acad Dermatol. 2015;S0190–9622(15):02124–6. [Epub ahead of print] PubMed PMID:26518173Google Scholar
  160. 160.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific Publications; 2012. p. 647–9.Google Scholar
  161. 161.
    Fetsch JF, Laskin WB, Miettinen M. Superficial acral fibromyxoma: a clinicopathologic and immunohistochemical analysis of 37 cases of a distinctive soft tissue tumor with a predilection for the fingers and toes. Hum Pathol. 2001;32(7):704–14.PubMedCrossRefGoogle Scholar
  162. 162.
    Hollmann TJ, Bovée JV, Fletcher CD. Digital fibromyxoma (superficial acral fibromyxoma): a detailed characterization of 124 cases. Am J Surg Pathol. 2012 Jun;36(6):789–98.PubMedCrossRefGoogle Scholar
  163. 163.
    Chattopadhyay M, Farrant P, Higgins E, Hay R, Calonje E. A nodular lesion of the toe. Superficial acral fibromyxoma (SAF). Clin Exp Dermatol. 2010 Oct;35(7):807–9.PubMedCrossRefGoogle Scholar
  164. 164.
    Sawaya JL, Khachemoune A. Superficial acral fibromyxoma. Int J Dermatol. 2015;54(5):499–508.PubMedCrossRefGoogle Scholar
  165. 165.
    Chabbab F, Metz T, Saez Beltran L, Theunis A, Richert B. Superficial acral fibromyxoma in a sub-matricial location: an unusual variant. Ann Dermatol Venereol. 2014;141(2):94–105.PubMedCrossRefGoogle Scholar
  166. 166.
    Kwok C, Merchant WJ, Hussain W. Superficial acral fibromyxoma presenting as a haemorrhagic pigmented streak on the toenail. Clin Exp Dermatol. 2013;38(5):553–4.CrossRefPubMedGoogle Scholar
  167. 167.
    Messeguer F, Nagore E, Agustí-Mejias A, Traves V. Superficial acral fibromyxoma: a CD34+ periungual tumor. Actas Dermosifiliogr. 2012;103(1):67–9.PubMedCrossRefGoogle Scholar
  168. 168.
    Schwager ZA, Mannava KA, Mannava S, Telang GH, Robinson-Bostom L, Jellinek NJ. Superficial acral fibromyxoma and other slow-growing tumors in acral areas. Cutis. 2015;95(2):E15–9.PubMedGoogle Scholar
  169. 169.
    Ashby-Richardson H, Rogers GS, Stadecker MJ. Superficial acral fibromyxoma: an overview. Arch Pathol Lab Med. 2011;135(8):1064–6.PubMedCrossRefGoogle Scholar
  170. 170.
    Gourdin FW, Lang PG Jr. Cylindrical deformity of the nail plate secondary to subungual myxoma. J Am Acad Dermatol. 1996;35(5 Pt 2):846–8.PubMedCrossRefGoogle Scholar
  171. 171.
    al-Qattan MM. Myxoma of the hand. J Hand Surg Br. 1996;21(5):690–2.PubMedCrossRefGoogle Scholar
  172. 172.
    Hill TL, Jones BE, Park KH. Myxoma of the skin of a finger. J Am Acad Dermatol. 1990;22(2 Pt 2):343–5.PubMedCrossRefGoogle Scholar
  173. 173.
    Cribier B, Baran R, Varini JP. Nerve sheath myxoma of the hyponychium. Ann Dermatol Venereol. 2013;140(8–9):535–9.PubMedCrossRefGoogle Scholar
  174. 174.
    Kaehr D, Klug MS. Subungual myxoma. J Hand Surg Am. 1986;11(1):73–6.PubMedCrossRefGoogle Scholar
  175. 175.
    Rozmaryn LM, Schwartz AM. Treatment of subungual myxoma preserving the nail matrix: a case report. J Hand Surg Am. 1998;23(1):178–80.PubMedCrossRefGoogle Scholar
  176. 176.
    Rakoto-Ratsimba HN, Razafimahandry HJ, Tsiaviry P, Rakototiana A, Rakotozafy G. Digital myxoma. A case report and review of the literature. Chir Main. 2005;24(5):270–2.PubMedCrossRefGoogle Scholar
  177. 177.
    Fierro-Arias L, Calderón L, Peniche-Castellanos A, Mercadillo-Pérez P. Periungual eccrine poroma. J Cutan Med Surg. 2014;18(5):1–3.PubMedGoogle Scholar
  178. 178.
    Noh S, Jin S, Lee N, Park CO, Chung KY, Lee KH. Eccrine poroma clinically mimicking ingrowing toenail complicated with granulation tissue. Ann Dermatol. 2013;25(2):247–8.PubMedPubMedCentralCrossRefGoogle Scholar
  179. 179.
    Al-Qattan MM, Al-Turaiki TM, Al-Oudah N, Arab K. Benign eccrine poroma of the dorsum of the hand: predilection for the nail fold and P53 positivity. J HandSurg Eur Vol. 2009;34(3):402–3.CrossRefGoogle Scholar
  180. 180.
    Casper DJ, Glass LF, Shenefelt PD. An unusually large eccrine poroma: a case report and review of the literature. Cutis. 2011;88(5):227–9.PubMedGoogle Scholar
  181. 181.
    Yoshioka N, Mukubo K, Isogai R, Yamada H. A case of eccrine poroma on the nail fold. Hifu no kagaku. 2013;12(1):35–8.Google Scholar
  182. 182.
    Robson A, Greene J, Ansari N, et al. Eccrine porocarcinoma (malignant eccrine poroma): a clinicopathologic study of 69 cases. Am J Surg Pathol. 2001;25:710–20.PubMedCrossRefGoogle Scholar
  183. 183.
    Mulinari-Brenner FA, Mukai MM, Bastos CA, Filho EA, Santamaria JR, Neto JF. Eccrine porocarcinoma: report of four cases and literature review. An Bras Dermatol. 2009;84(5):519–23.PubMedCrossRefGoogle Scholar
  184. 184.
    Brown CW Jr, Dy LC. Eccrine porocarcinoma. Dermatol Ther. 2008;21(6):433–8.PubMedCrossRefGoogle Scholar
  185. 185.
    Dominguez-Cherit J, Brandariz A. Distal digital angioleiomyoma: a case report and review of the literature. Int J Dermatol. 2003;42(2):141–3.PubMedCrossRefGoogle Scholar
  186. 186.
    Albares MP, Belinchón I, Vergara G, Pascual JC, Pastor E. Digital angioleiomyoma. Int J Dermatol. 2002;41(8):527.PubMedCrossRefGoogle Scholar
  187. 187.
    del Olmo J, Marquina M, Redondo P. Asymptomatic digital angioleiomyoma. Actas Dermosifiliogr. 2007;98(4):292–3.PubMedCrossRefGoogle Scholar
  188. 188.
    Hachisuga T, Hashimoto H, Enjoji M. Angioleiomyoma. A clinicopathologic reappraisal of 562 cases. Cancer. 1984;54(1):126–30.PubMedCrossRefGoogle Scholar
  189. 189.
    Baran R, Requena L, Drapé JL. Subungual angioleiomyoma masquerading as a glomus tumour. Br J Dermatol. 2000;142(6):1239–41.PubMedCrossRefGoogle Scholar
  190. 190.
    Watson J, Gonzalez M, Romero A, Kerns J. Neuromas of the hand and upper extremity. J Hand Surg Am. 2010;35(3):499–510.PubMedCrossRefGoogle Scholar
  191. 191.
    Vernadakis AJ, Koch H, Mackinnon SE. Management of neuromas. Clin Plast Surg. 2003;30(2):247–68.PubMedCrossRefGoogle Scholar
  192. 192.
    Rashid RM, Rashid RM, Thomas V. Subungal traumatic neuroma. J Am Acad Dermatol. 2010;63(1):7–8.CrossRefGoogle Scholar
  193. 193.
    Chen KH, Lee KF, Hsu HC, Huang WC, Hsiao KY, Fang KM. The role of high-resolution ultrasound in the diagnosis of a traumatic neuroma in an injured median nerve. Am J Phys Med Rehabil. 2009;88(9):771–4.PubMedCrossRefGoogle Scholar
  194. 194.
    Ahlawat S, Belzberg AJ, Montgomery EA, Fayad LM. MRI features of peripheral traumatic neuromas. Eur Radiol. 2015 Jul 19. [Epub ahead of print] PubMed PMID: 26188658.Google Scholar
  195. 195.
    Kakinoki R, Ikeguchi R, Atiyya AN, Nakamura T. Treatment of posttraumatic painful neuromas at the digit tip using neurovascular island flaps. J Hand Surg Am. 2008;33(3):348–52.PubMedCrossRefGoogle Scholar
  196. 196.
    Narayanamurthy V, Winston AT, Gupta A. A rare case of Pacinian corpuscle neuroma. Can J Plast Surg. 2005;13(1):43–5.PubMedPubMedCentralCrossRefGoogle Scholar
  197. 197.
    Kenmochi A, Satoh T, Fukuyama K, Yokozeki H. Pacinian neuroma. J Eur Acad Dermatol Venereol. 2006;20(10):1384–5.PubMedCrossRefGoogle Scholar
  198. 198.
    Mahipathy SR, Durairaj AR, Parthasarathy J. Pacinian neuroma presenting as congenital macrodactyly: a rare case report. J Clin Diagn Res. 2015;9(9):PD22–3.  https://doi.org/10.7860/JCDR/2015/14525.6528. Epub 2015 Sep 1CrossRefPubMedPubMedCentralGoogle Scholar
  199. 199.
    McPherson SA, Meals RA. Digital pacinian corpuscle neuroma eroding bone a case report. J Hand Surg Am. 1992;17(3):476–8.PubMedCrossRefGoogle Scholar
  200. 200.
    Zanardi F, Cooke RM, Maiorana A, Curti S, Farioli A, Bonfiglioli R, Violante FS, Mattioli S. “Is this case of a very rare disease work-related?” A review of reported cases of Pacinian neuroma. Scand J Work Environ Health. 2011;37(3):253–8.PubMedCrossRefGoogle Scholar
  201. 201.
    Moon SE, Cho YJ, Kwon OS. Subungual schwannoma: a rare location. Dermatol Surg. 2005;31(5):592–4.CrossRefPubMedGoogle Scholar
  202. 202.
    Kulkarni J, Moholkar A, Patil A. Subungual schwannoma: an uncommon location. J Hand Surg Am. 2013;38(6):1258–9.PubMedCrossRefGoogle Scholar
  203. 203.
    Kransdorf MJ. Benign soft-tissue tumors in a large referral population: distribution of specific diagnoses by age, sex, and location. AJR Am J Roentgenol. 1995;164(2):395–402.PubMedCrossRefGoogle Scholar
  204. 204.
    Huntley JS, Davie RM, Hooper G. A subungual schwannoma. Plast Reconstr Surg. 2006;117(2):712–3.PubMedCrossRefGoogle Scholar
  205. 205.
    Dwyer CL, Creager AJ, Lubahn JD. An unusual presentation of a digital schwannoma: case report. Hand (N Y). 2015;10(2):301–4.CrossRefGoogle Scholar
  206. 206.
    Lai CS, Chen IC, Lan HC, Lu CT, Yen JH, Song DY, Tang YW. Management of extremity neurilemmomas: clinical series and literature review. Ann Plast Surg. 2013;71(Suppl 1):S37–42.PubMedGoogle Scholar
  207. 207.
    Ozdemir O, Ozsoy MH, Kurt C, Coskunol E, Calli I. Schwannomas of the hand and wrist: long-term results and review of the literature. J Orthop Surg (Hong Kong). 2005;13(3):267–72. Review. Erratum in: J Orthop Surg (Hong Kong). 2006;14(2):following 229.PubMedCrossRefGoogle Scholar
  208. 208.
    Wippold FJ 2nd, Lubner M, Perrin RJ, Lämmle M, Perry A. Neuropathology for the neuroradiologist: Antoni A and Antoni B tissue patterns. AJNR Am J Neuroradiol. 2007;28(9):1633–8.PubMedCrossRefGoogle Scholar
  209. 209.
    Joshi R. Learning from eponyms: Jose Verocay and Verocay bodies, Antoni A and B areas, Nils Antoni and Schwannomas. Indian Dermatol Online J. 2012;3(3):215–9.PubMedPubMedCentralCrossRefGoogle Scholar
  210. 210.
    Ishida N, Watanabe D, Yokoo K, Tamada Y, Matsumoto Y. Schwannoma of a digit. Eur J Dermatol. 2006;16(4):453–4.PubMedGoogle Scholar
  211. 211.
    Richert B, André J, Choffray A, Rahier S, de la Brassinne M. Periungual lipoma: about three cases. J Am Acad Dermatol. 2004;51(2 Suppl):S91–3.PubMedCrossRefGoogle Scholar
  212. 212.
    Vélez NF, Telang GH, Robinson-Bostom L, Jellinek NJ. Subungual lipoma: presenting as longitudinal nail splitting. Dermatol Surg. 2014;40(12):1435–7.PubMedCrossRefGoogle Scholar
  213. 213.
    Ait-Ourhrouil M, Grosshans E. Peri-sudoral lipoma. Ann Dermatol Venereol. 1997;124:845–8.PubMedGoogle Scholar
  214. 214.
    Khan PS, Hayat H. Lipoma of the middle finger hampering its movements. J Hand Microsurg. 2011;3(1):42–3.PubMedPubMedCentralCrossRefGoogle Scholar
  215. 215.
    Kitagawa Y, Tamai K, Kim Y, Hayashi M, Makino A, Takai S. Lipoma of the finger with bone erosion. J Nippon Med Sch. 2012;79(4):307–11.PubMedCrossRefGoogle Scholar
  216. 216.
    Bardazzi F, Savoia F, Fanti PA. Subungual lipoma. Br J Dermatol. 2003;149(2):418.PubMedCrossRefGoogle Scholar
  217. 217.
    Wortsman XC, Holm EA, Wulf HC, Jemec GB. Real-time spatial compound ultrasound imaging of skin. Skin Res Technol. 2004;10(1):23–31.PubMedCrossRefGoogle Scholar
  218. 218.
    Thomas L, Zook EG, Haneke E, Drapé J, Baran R, Kreusch JF. Tumors of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, de Berker DAR, et al., editors. Nail diseases and their management. 4th ed. Oxford: Blackwell Scientific; 2012. p. 700.Google Scholar
  219. 219.
    Kwon NH, Kim HS, Kang H, Lee JY, Kim HO, Kang SJ, Park YM. Subungual spindle cell lipoma. Int J Dermatol. 2013;52(5):636–8.PubMedCrossRefGoogle Scholar
  220. 220.
    González-Rodríguez AJ, Gutiérrez-Paredes EM, Montesinos-Villaescusa E, Burgués Gasión O, Jordá-Cuevas E. Subungual keratoacanthoma: the importance of distinguishing it from subungual squamous cell carcinoma. Actas Dermosifiliogr. 2012;103(6):549–51.PubMedCrossRefGoogle Scholar
  221. 221.
    Choi JH, Shin DH, Shin DS, et al. Subungual keratoacanthoma: ultrasound and magnetic resonance imaging findings. Skelet Radiol. 2007;36:769–72.CrossRefGoogle Scholar
  222. 222.
    Connolly M, Narayan S, Oxley J, de Berker DA. Immunohistochemical staining for the differentiation of subungual keratoacanthoma from subungual squamous cell carcinoma. Clin Exp Dermatol. 2008;33(5):625–8.PubMedCrossRefGoogle Scholar
  223. 223.
    Cecchi R, Troiano M, Buralli L, Innocenti S. Recurrent distal digital keratoacanthoma of the periungual region treated with Mohs micrographic surgery. Australas J Dermatol. 2012;53(1):e5–7.PubMedCrossRefGoogle Scholar
  224. 224.
    Krull EA. Epidermoid carcinoma of the subungual and periungual tissues. In: Krull EA, Zook EG, Baran R, Haneke E, editors. Nail surgery: a text and atlas. Philadelphia: Lippincott Williams and Wilkins; 2001. p. 297–303.Google Scholar
  225. 225.
    Riddel C, Rashid R, Thomas V. Ungual and periungual human papillomavirus-associated squamous cell carcinoma: a review. J Am Acad Dermatol. 2011;64:1147–53.PubMedCrossRefGoogle Scholar
  226. 226.
    Valero J, Gallart J, Gonzalez D, Deus J, Lahoz M. Subungual squamous cell carcinoma and exostosis in third toe–case report and literature review. J Eur Acad Dermatol Venereol. 2014;28(10):1292–7.PubMedCrossRefGoogle Scholar
  227. 227.
    Baran RL, Gormley DE. Polydactylous Bowen’s disease of the nail. J Am Acad Dermatol. 1987;17(2 Pt 1):201–4.PubMedCrossRefGoogle Scholar
  228. 228.
    Goodman G, Mason G, O’Brien T. Polydactylous Bowen’s disease of the nail bed. Australas J Dermatol. 1995;36:164–5.PubMedCrossRefGoogle Scholar
  229. 229.
    Potter JA, Griffin PA. Polydactylous subungual squamous cell carcinoma caused by chemical contact. Plast Reconstr Surg Glob Open. 2013;1(4):e28.PubMedPubMedCentralCrossRefGoogle Scholar
  230. 230.
    Patel PP, Hoppe IC, Bell WR, Lambert WC, Fleegler EJ. Perils of diagnosis and detection of subungual squamous cell carcinoma. Ann Dermatol. 2011;23(Suppl 3):S285–7. Indian J Dermatol. 2014 Jul-Aug; 59(4): 352–4.PubMedPubMedCentralCrossRefGoogle Scholar
  231. 231.
    Tang N, Maloney ME, Clark AH, Jellinek NJ. A retrospective study of nail squamous cell carcinoma at 2 institutions. Dermatol Surg. 2016;42(Suppl 1):S8–S17.CrossRefPubMedGoogle Scholar
  232. 232.
    Ohishi K, Nakamura Y, Ohishi Y, Yokomizo E, Ohara K, Takasaki M, Ueno T, Kawana S, Mitsuishi T. Bowen’s disease of the nail apparatus and association with various high-risk human papillomavirus types. J Dermatol Sci. 2011;63(1):69–72.PubMedCrossRefGoogle Scholar
  233. 233.
    Matoso A, Jellinek N, Telang GH. Verrucous carcinoma of the nail unit. Am J Dermatopathol. 2012;34:e106–10.PubMedCrossRefGoogle Scholar
  234. 234.
    Baran R, Simon C. Longitudinal melanonychia: a symptom of Bowen’s disease. J Am Acad Dermatol. 1988;18:1359–60.PubMedCrossRefGoogle Scholar
  235. 235.
    Wortsman X. Métodos de imagens nas unhas. In: Di Chiacchio N, Belda Jr W, Criado PR, editors. Unhas: o que há de novo. Rio de Janeiro: Ed Atheneu; 2015. p. 11–5.Google Scholar
  236. 236.
    André J, Sass U, Richert B, Theunis A. Nail pathology. Clin Dermatol. 2013;31(5):526–39.PubMedCrossRefGoogle Scholar
  237. 237.
    Batalla A, Feal C, Rosón E, Posada C. Subungual squamous cell carcinoma: a case series. Indian J Dermatol. 2014;59(4):352–4.PubMedPubMedCentralCrossRefGoogle Scholar
  238. 238.
    Ormerod E, de Berker D. Nail unit squamous cell carcinoma in people with immunosuppression. Br J Dermatol. 2015;173(3):701–12.CrossRefPubMedGoogle Scholar
  239. 239.
    Laffitte E, Saurat J-H. Recurrent Bowen’s disease of the nail: treatment by topical imiquimod (Aldara). Ann Dermatol Venereol. 2003;130(2 Pt 1):211–3.PubMedGoogle Scholar
  240. 240.
    Sau P, McMarlin SL, Sperling LC, et al. Bowen’s disease of the nail bed and periungual area. A clinicopathologic analysis of seven cases. Arch Dermatol. 1994;130:204–9.CrossRefPubMedGoogle Scholar
  241. 241.
    Nordin P, Stenquist BC. Aggressive curettage-cryosurgery for human papillomavirus-16 associated subungual squamous cell carcinoma in situ. J Cutan Aesthet Surg. 2013;6(3):155–7.PubMedPubMedCentralCrossRefGoogle Scholar
  242. 242.
    Usmani N, Stables GI, Telfer NR, et al. Subungual Bowen’s disease treated by topical aminolevulinic acid-photodynamic therapy. J Am Acad Dermatol. 2005;53(5 Suppl 1):S273–6.CrossRefPubMedGoogle Scholar
  243. 243.
    Sheen Y-S, Sheen M-C, Sheu H-M, et al. Squamous cell carcinoma of the big toe successfully treated by intra-arterial infusion with methotrexate. Dermatol Surg. 2003;29:982–3.PubMedGoogle Scholar
  244. 244.
    Arterbery VE, Watson AC. An electronic brachytherapy technique for treating squamous cell carcinoma in situ of the digit: a case report. BMC Res Notes. 2013;6:147.PubMedPubMedCentralCrossRefGoogle Scholar
  245. 245.
    Rosen LR, Powell K, Katz SR, Wu HT, Durci M. Subungual squamous cell carcinoma: radiation therapy as an alternative to amputation and review of the literature. Am J Clin Dermatol. 2010;11(4):285–8.PubMedGoogle Scholar
  246. 246.
    Dika E, Fanti PA, Patrizi A, Misciali C, Vaccari S, Piraccini BM. Mohs surgery for squamous cell carcinoma of the nail unit: 10 years of experience. Dermatol Surg. 2015;41(9):1015–9.PubMedGoogle Scholar
  247. 247.
    Bandyopadhyay D, Sen S. Periungual Basal cell carcinoma: a case report with review of literature. Indian J Dermatol. 2011;56(2):220–2.PubMedPubMedCentralCrossRefGoogle Scholar
  248. 248.
    Forman SB, Ferringer TC, Garrett AB. Basal cell carcinoma of the nail unit. J Am Acad Dermatol. 2007;56(5):811–4.PubMedCrossRefGoogle Scholar
  249. 249.
    Grine RC, Parlette HL 3rd, Wilson BB. Nail unit basal cell carcinoma: a case report and literature review. J Am Acad Dermatol. 1997;37(5 Pt 1):790–3.PubMedCrossRefGoogle Scholar
  250. 250.
    Engel E, Ulrich H, Vasold R, König B, Landthaler M, Süttinger R, Bäumler W. Azo pigments and a basal cell carcinoma at the thumb. Dermatology. 2008;216(1):76–80.PubMedCrossRefGoogle Scholar
  251. 251.
    Potier A, Avenel Audran M, Belperron P, Briand E, Croue A, Verret JL. Basal cell carcinoma of the first toenail. Ann Dermatol Venereol. 2007;134(10 Pt 1):757–9.PubMedCrossRefGoogle Scholar
  252. 252.
    Martinelli PT, Cohen PR, Schulze KE, Dorsey KE, Nelson BR. Periungual basal cell carcinoma: case report and literature review. Dermatol Surg. 2006;32(2):320–3.PubMedGoogle Scholar
  253. 253.
    de Giorgi V, Salvini C, Massi D, Sestini S, Difonzo E, Carli P. Ungual basal cell carcinoma on the fifth toe mimicking chronic dermatitis: case study. Dermatol Surg. 2005;31(6):723–5.PubMedCrossRefGoogle Scholar
  254. 254.
    Matsushita K, Kawada A, Aragane Y, Tezuka T. Basal cell carcinoma on the right hallux. J Dermatol. 2003;30(3):250–1.PubMedCrossRefGoogle Scholar
  255. 255.
    Herzinger T, Flaig M, Diederich R, Röcken M. Basal cell carcinoma of the toenail unit. J Am Acad Dermatol. 2003;48(2):277–8.PubMedCrossRefGoogle Scholar
  256. 256.
    Orsini RC, Catanzariti A, Saltrick K, Mendicino RW, Stokar L. Basal cell carcinoma of the nail unit: a case report. Foot Ankle Int. 2001;22(8):675–8.PubMedCrossRefGoogle Scholar
  257. 257.
    Moussallem CD, Abi Hatem NE, El-Khoury ZN. Malignant porocarcinoma of the nail fold: a tricky diagnosis. Dermatol Online J. 2008;14(8):10.PubMedGoogle Scholar
  258. 258.
    Engel CJ, Meads GE, Joeph NG, Stavrasky W. Eccrine spiradenoma: a report of malignant transformation. Can J Surg. 1991;34:477–80.PubMedGoogle Scholar
  259. 259.
    Requena L, Sanchez M, Aguilar A, et al. Periungaual porocarcinoma. Dermatologica. 1990;180:177–80.Google Scholar
  260. 260.
    van Gorp J, van der Putte SC. Periungual eccrine porocarcinoma. Dermatology. 1993;187(1):67–70.PubMedCrossRefGoogle Scholar
  261. 261.
    Bhat W, Akhtar S, Khotwal A, Platt AJ. Primary eccrine porocarcinoma of the finger with transit forearm and axillary metastasis. Ann Plast Surg. 2011;66(4):344–6.PubMedCrossRefGoogle Scholar
  262. 262.
    Goldenhersh MA, Prus D, Ron N, Rosenmann E. Merkel cell tumor masquerading as granulation tissue on a teenager's toe. Am J Dermatopathol. 1992;14(6):560–3.PubMedCrossRefGoogle Scholar
  263. 263.
    Helmbold P, Schröter S, Holzhausen HJ, Hartschuh W, Marsch WC. Merkel cellcarcinoma: a diagnostic and therapeutic challenge. Chirurg. 2001;72(4):396–401.PubMedCrossRefGoogle Scholar
  264. 264.
    Kobayashi T, Hiura A, Oishi K, Maeda S, Le Pavoux AJ, Ohara K, Uruga H. Aggressive digital papillary adenocarcinoma with multiple organ metastases: a case report and review of the literature. Am J Dermatopathol. 2016;38(12):910–4.PubMedPubMedCentralCrossRefGoogle Scholar
  265. 265.
    Nash M, Burn J, Chan S. An unexpected digital papillary adenocarcinoma of the thumb. Case Reports Plast Surg Hand Surg. 2016;3(1):77–8.PubMedPubMedCentralCrossRefGoogle Scholar
  266. 266.
    Krishnamurthy J, Patil B. Aggressive digital papillary adenocarcinoma diagnosed by fine needle aspiration cytology. J Cytol. 2010;27(3):109–11.PubMedPubMedCentralCrossRefGoogle Scholar
  267. 267.
    Kempton SJ, Navarrete AD, Salyapongse AN. Aggressive digital papillary adenocarcinoma: case report of a positive sentinel lymph node and discussion of utility of sentinel lymph node biopsy. Ann Plast Surg. 2015;75(1):34–6.PubMedCrossRefGoogle Scholar
  268. 268.
    Cohen PR. Metastatic tumors to the nail unit: subungual metastases. Dermatol Surg. 2001;27(3):280–93.PubMedGoogle Scholar
  269. 269.
    Thomas L, Zook EG, Haneke E, Drapé JL, Baran R. Tumours of the nail apparatus and adjacent tissues. In: Baran R, Dawber RPR, editors. Diseases of the nails and their management. 4th ed. Oxford: Blackwell Scientific; 2012. p. 711–2.Google Scholar
  270. 270.
    Babacan NA, Kiliçkap S, Sene S, Kacan T, Yucel B, Eren MF, Cihan S. A case of multifocal skin metastases from lung cancer presenting with vasculitic-type cutaneous nodule. Indian J Dermatol. 2015;60(2):213.PubMedPubMedCentralGoogle Scholar
  271. 271.
    Vanhooteghem O, Dumont M, André J, Leempoel M, de la Brassinne M. Bilateral subungual metastasis from squamous cell carcinoma of the lung: a diagnostic trap! Rev Med Liege. 1999;54(8):653–4.PubMedGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Nilton Di Chiacchio
    • 1
  • Nilton Gioia Di Chiacchio
    • 1
  • Leandro Fonseca Noriega
    • 1
  1. 1.Dermatologic Clinic of Hospital do Servidor Público MunicipalSao PauloBrazil

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