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Nail Reactions to Antibiotics, Antimalarials, and Other Medications

  • John Montgomery YostEmail author

Abstract

Many drug classes have been associated with drug-induced nail abnormalities, including antimicrobials, antimalarials, cardiovascular agents, anti-inflammatories, antirheumatics, hormones, neuropsychiatric medications, as well as other agents. The specific nail dystrophies changes that result with each individual agent is determined by the portion of the nail apparatus affected. Photoonycholysis, chromonychia, dyspigmentation of the nail unit, altered growth rate, Beaus’s lines, onychomadesis, paronychia, and periungual pyogenic granulomas represent many common sequelae associated with systemic therapy. These subsequent drug-related dystrophies are often largely asymptomatic and self-limited, however are nonetheless important for clinicians to recognize.

Keywords

Drug induced nail changes Photoonycholysis Onycholysis Chromonychia Melanonychia Xanthonychia Leukonychia Beau’s lines Onychomadesis Red lunulae Blue lunulae Nail growth rate Paronychia Pyogenic granuloma Onychocryptosis 

Supplementary material

978-3-319-65649-6_28_MOESM1_ESM.pdf (31 kb)
Patient Handout (PDF 30 kb)

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© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Nail Disorders Clinic, Department of Dermatology, Stanford University School of MedicineStanfordUSA

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