Radiobiology of Stereotactic Radiosurgery in the Treatment of Arteriovenous Malformations
Stereotactic radiosurgery (SRS) has been defined as the use of concentrated ionizing radiation delivered to a stereotactically defined point in space [1, 2]. SRS was used to treat patients with arteriovenous malformations (AVMs) as early as the 1970s . As many as 500,000 people in North America have AVMs . With SRS, angiographic cures fall between 60 and 90% [3–5]. A consideration of the radiobiology of SRS will explain why tumors and vascular lesions respond to radiation differently, and why patients with AVMs are ideal candidates for radiosurgery.
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