Abstract
Advances in interventional techniques have revolutionized the treatment of congenital vascular malformations of all types. Traditional open surgical extirpation of these lesions carries the very real risks of excessive blood loss, incomplete excision of the lesions—often resulting in recurrent pathology—wound-healing complications, and frequently suboptimal aesthetic outcomes. While surgery is still indicated in some cases, interventional treatments have far and away become the first-line approach in a nearly universal paradigm shift toward less invasive techniques that also typically result in diminished associated morbidity.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Love Z, Hsu DP. Low-flow vascular malformations of the head and neck: clinicopathology and image guided therapy. J Neurointerv Surg. 2012;4(6):414–25.
Berenguer B, Burrows PE, Zurakowski D, Mulliken JB. Sclerotherapy of craniofacial venous malformations: complications and results. Plast Reconstr Surg. 1999;104(1):1–11. Discussion 2–5.
Mason KP, Michna E, Zurakowski D, Koka BV, Burrows PE. Serum ethanol levels in children and adults after ethanol embolization or sclerotherapy for vascular anomalies. Radiology. 2000;217(1):127–32.
Lee BB, Do YS, Byun HS, Choo IW, Kim DI, Huh SH. Advanced management of venous malformation with ethanol sclerotherapy: mid-term results. J Vasc Surg. 2003;37(3):533–8.
Sainsbury DC, Kessell G, Fall AJ, Hampton FJ, Guhan A, Muir T. Intralesional bleomycin injection treatment for vascular birthmarks: a 5-year experience at a single United Kingdom unit. Plast Reconstr Surg. 2011;127(5):2031–44.
Spence J, Krings T, terBrugge KG, da Costa LB, Agid R. Percutaneous sclerotherapy for facial venous malformations: subjective clinical and objective MR imaging follow-up results. AJNR Am J Neuroradiol. 2010;31(5):955–60.
Spence J, Krings T, TerBrugge KG, Agid R. Percutaneous treatment of facial venous malformations: a matched comparison of alcohol and bleomycin sclerotherapy. Head Neck. 2011;33(1):125–30.
Tan KT, Kirby J, Rajan DK, Hayeems E, Beecroft JR, Simons ME. Percutaneous sodium tetradecyl sulfate sclerotherapy for peripheral venous vascular malformations: a single-center experience. J Vasc Interv Radiol. 2007;18(3):343–51.
O’Donovan JC, Donaldson JS, Morello FP, Pensler JM, Vogelzang RL, Bauer B. Symptomatic hemangiomas and venous malformations in infants, children, and young adults: treatment with percutaneous injection of sodium tetradecyl sulfate. AJR Am J Roentgenol. 1997;169(3):723–9.
Tieu DD, Ghodke BV, Vo NJ, Perkins JA. Single-stage excision of localized head and neck venous malformations using preoperative glue embolization. Otolaryngol Head Neck Surg. 2013;148(4):678–84.
Mazoyer E, Enjolras O, Laurian C, Houdart E, Drouet L. Coagulation abnormalities associated with extensive venous malformations of the limbs: differentiation from Kasabach-Merritt syndrome. Clin Lab Haematol. 2002;24:243–51.
Mazoyer E, Enjolras O, Bisdorff A, Perdu J, Wassef M, Drouet L. Coagulation disorders in patients with venous malformations of the limbs and trunk. Arch Dermatol. 2008;144(7):861–7.
Dompmartin A, Acher A, Thibon P, et al. Association of localized intravascular coagulopathy with venous malformations. Arch Dermatol. 2008;144(7):873–7.
Burrows PE, Mitri RK, Alomari A, et al. Percutaneous sclerotherapy of lymphatic malformations with doxycycline. Lymphat Res Biol. 2008;6(3–4):209–16.
Nehra D, Jacobson L, Barnes P, Mallory B, Albanese CT, Sylvester KG. Doxycycline sclerotherapy as primary treatment of head and neck lymphatic malformations in children. J Pediatr Surg. 2008;43(3):451–60.
Acevedo JL, Shah RK, Brietzke SE. Nonsurgical therapies for lymphangiomas: a systematic review. Otolaryngol Head Neck Surg. 2008;138(4):418–24.
Do YS, Yakes WF, Shin SW, et al. Ethanol embolization of arteriovenous malformations: interim results. Radiology. 2005;235(2):674–82.
Lee BB, Baumgartner I, Berlien HP, et al. Consensus document of the International Union of Angiology (IUA)-2013. Current concept on the management of arterio-venous management. Int Angiol. 2013;32(1):9–36.
Yakes WF, Rossi P, Odink H. How I do it. Arteriovenous malformation management. Cardiovasc Intervent Radiol. 1996;19(2):65–71.
Yakes WF. Endovascular management of high-flow arteriovenous malformations. Semin Intervent Radiol. 2004;21(1):49–58.
Thiex R, Wu I, Mulliken JB, Greene AK, Rahbar R, Orbach DB. Safety and clinical efficacy of onyx for embolization of extracranial head and neck vascular anomalies. AJNR Am J Neuroradiol. 2011;32(6):1082–6.
Pekkola J, Lappalainen K, Vuola P, Klockars T, Salminen P, Pitkaranta A. Head and neck arteriovenous malformations: results of ethanol sclerotherapy. AJNR Am J Neuroradiol. 2013;34(1):198–204.
Benndorf G, Campi A, Hell B, Holzle F, Lund J, Bier J. Endovascular management of a bleeding mandibular arteriovenous malformation by transfemoral venous embolization with NBCA. AJNR Am J Neuroradiol. 2001;22(2):359–62.
Fan XD, Su LX, Zheng JW, Zheng LZ, Zhang ZY. Ethanol embolization of arteriovenous malformations of the mandible. AJNR Am J Neuroradiol. 2009;30(6):1178–83.
Zheng LZ, Fan XD, Zheng JW, Su LX. Ethanol embolization of auricular arteriovenous malformations: preliminary results of 17 cases. AJNR Am J Neuroradiol. 2009;30(9):1679–84.
Clarencon F, Blanc R, Lin CJ, et al. Combined endovascular and surgical approach for the treatment of palpebral arteriovenous malformations: experience of a single center. AJNR Am J Neuroradiol. 2012;33(1):148–53.
Arat A, Cil BE, Vargel I, et al. Embolization of high-flow craniofacial vascular malformations with onyx. AJNR Am J Neuroradiol. 2007;28:1409–14.
Zheng LZ, Fan XD, Zheng JW, Su LX. AJNR Am J Neuroradiol. 2009;30(9):1679–84. doi: 10.3174/ajnr.A1687. Epub 2009 Jul 17
Dabus G, Linfante I, Benenati J, Perlyn CA, Martínez-Galdámez M. Interventional management of high-flow craniofacial vascular malformations: a database analysis and review of the literature. J Neurointerv Surg. 2017;9(1):92–6.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Stalder, M.W., Perlyn, C.A., Dabus, G. (2018). Sclerotherapy of Vascular Malformations. In: Gandhi, C., Prestigiacomo, C. (eds) Cerebrovascular and Endovascular Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-319-65206-1_33
Download citation
DOI: https://doi.org/10.1007/978-3-319-65206-1_33
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-65204-7
Online ISBN: 978-3-319-65206-1
eBook Packages: MedicineMedicine (R0)