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Cerebral Amyloid Angiopathy with Alzheimer’s Disease

  • Robert MatthewsEmail author
Chapter

Abstract

Cerebral amyloid angiopathy is a disease characterized by the deposition of β-amyloid in small and medium size arteries of the cerebral cortex and leptomeninges leading to microaneurysm formation and subsequent bleeding. Cerebral amyloid angiopathy is closely associated with Alzheimer’s disease which is well detected on PET/MR imaging.

Keywords

Cerebral amyloid angiopathy Alzheimer’s disease of β-amyloid Amyloid plaque imaging Siderosis Microaneurysm Intracranial hemorrhage Small vessel disease FDG PET/MR 

Suggested Reading

  1. Baron JC, Farid K, Dolan E, Turc G, Marrapu ST, O'Brien E, et al. Diagnostic utility of amyloid PET in cerebral amyloid angiopathy-related symptomatic intracerebral hemorrhage. J Cereb Blood Flow Metab. 2014;34(5):753–8.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Chao CP, Kotsenas AL, Broderick DF. Cerebral amyloid angiopathy: CT and MR imaging findings. Radiographics. 2006;26(5):1517–31.CrossRefPubMedGoogle Scholar
  3. Drzezga A, Barthel H, Minoshima S, Sabri O. Potential clinical applications of PET/MR imaging in neurodegenerative diseases. J Nucl Med. 2014;55(Suppl 2):47S–55S.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Department of RadiologyStony Brook University HospitalStony BrookUSA

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