Vitiligo pp 463-468 | Cite as

Discussion on Empirical, Traditional, and Alternative Treatments

  • Mauro PicardoEmail author


Alternative treatments, such as traditional Chinese products, plant-derived photosensitizing agents, and herbal and vitamin supplements, can certainly improve therapeutic outcomes in vitiligo.

Traditional Chinese medicine is currently attracting interest in dermatological research looking at the possible development of new drugs. This approach is supported by the political strategies of Western medicine community toward China.

The pro-melanogenic effect may be related to antioxidant or anti-inflammatory properties; however, the main limitation of the published studies concerns the non-complete list of the used products as well as their chemical composition. Similarly, the effectiveness of melagenin is still lacking the knowledge of the underlying mechanisms of repigmentation. On the basis of the in vitro study on immunomodulatory action, aspirin and statins may be considered for the treatment.

More controlled studies should be performed before considering most of the new emerging options based on unconventional drug or combinatory approaches.


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Cutaneous Physiopathology and CIRMSan Gallicano Dermatological Institute, IRCCSRomeItaly

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