Mesothelioma and Thymic Tumors
This chapter will discuss the workup and management of mesothelioma and thymic tumors, with an emphasis on external beam radiotherapy technique and published evidence.
KeywordsMesothelioma Thymoma Thymic carcinoma Radiation therapy
We thank Fred Y. Wu MD, PhD, Brian Lee MD, PhD, and Joycelyn L. Speight MD, PhD for their work on the prior edition of this chapter.
- Clive A, Taylor H, Dobson L, et al. Prophylactic radiotherapy for the prevention of procedure-tract metastases after surgical and large-bore pleural procedures in malignant pleural mesothelioma (SMART): a multicenter, open-label, phase 3, randomized controlled trial. Lancet Oncol. 2016;17(8):1094–104.CrossRefGoogle Scholar
- Komaki R, Travis EL, Cox JD. The lung and thymus. In: Cox JD, Ang KK, editors. Radiation oncology: rationale, technique, results. 8th ed. St. Louis: Mosby; 2003. p. 399–427.Google Scholar
- Krayenbuhl J, OErtel S, Davis JB, et al. Combined photon and electron three-dimensional conformal versus intensity-modulated radiotherapy with integrated boost for adjuvant treatment of malignant pleural mesothelioma after pleuropneumectomy. Int J Radiat Oncol Biol Phys. 2007;69(5):1593–9.CrossRefGoogle Scholar
- Treasure T, Lang-Lazdunski L, Waller D, et al. Extra-pleural pneumonectomy vs no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the mesothelioma and radical surgery (MARS) randomized feasibility study. Lancet Oncol. 2011;12(8):763–72.CrossRefGoogle Scholar