Acute Peripheral Arterial Disease

  • Francesco Speziale
  • Pasqualino SirignanoEmail author
  • Simone Cuozzo
  • Wassim Mansour
  • Chiara Pranteda
  • Martina Formiconi
  • Alessandro d’Adamo
  • Laura Capoccia


Acute limb ischemia (ALI) is a pathological condition resulting from a sudden blood interruption (or, at least, from an important reduction in flow) limiting tissues’ survival. ALI is always a serious event requiring immediate diagnosis and treatment, also considering the high associated amputation risk. The most frequent causes of acute limb ischemia are embolism, thrombosis, and trauma. Clinical findings are grouped together in a series mnemonic note as “6P of Pratt”: pain, pallor, pulselessness, poikilothermia, paresthesia, and paralysis. Those in concert with duplex ultrasound assume a primary and crucial role in diagnostic and preoperative evaluation of ALI patients. Treatment for ALI largely depends on the clinical presentation according to Rutherford’s classification. When indication for surgery is posed, several open, endovascular, and hybrid procedures are developed to restore blood flow in acute patients.


Acute limb ischemia ALI Embolectomy Aspiration system Vacuum therapy Hybrid surgery 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Francesco Speziale
    • 1
  • Pasqualino Sirignano
    • 1
    Email author
  • Simone Cuozzo
    • 1
  • Wassim Mansour
    • 1
  • Chiara Pranteda
    • 1
  • Martina Formiconi
    • 1
  • Alessandro d’Adamo
    • 1
  • Laura Capoccia
    • 1
  1. 1.Vascular and Endovascular Surgery, Department of Surgery “Paride Stefanini”“Policlinico Umberto I”, “Sapienza” Università di RomaRomeItaly

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