Introduction to Gastrointestinal Diseases Vol. 2 pp 167-176 | Cite as
Patient’s Guide in Colorectal Cancer: Observation After Treatment and Treatment of Relapse
Abstract
Surgery is a first-line treatment in up to 80% of patients with newly diagnosed colorectal cancer (CRC), as in most cases they present locoregional disease spread. Most patients undergo follow-up after treatment, in purpose to detect relapse and/or existence of metachronous lesions. Other benefits of surveillance are monitoring for side effects of therapy, detection of other comorbidities, as well as the psychological aspect of prolonged medical care. However, follow-up strongly depends on stage as well as perioperative treatment, and its intensity remains a matter of great controversy worldwide. In this section we will present a general review of different surveillance strategies regarding the role of endoscopic examination, diagnostic-imaging techniques, as well as fecal and serum tests in post-CRC surveillance. Presented recommendations do not include a matter of surveillance in patients with familial cancer syndromes that have not undergone total proctocolectomy.
Keywords
Colorectal cancer Adenoma Surveillance Proctocolectomy Risk of relapse Colonoscopy Radiotherapy ChemotherapyAbbreviations
- CRC
Colorectal cancer
- CT
Computed tomography
- CTC
Computed tomographic colonography
- ESMO
European Society for Medical Oncology
- MRI
Magnetic resonance imaging
- PET/CT
Positron emission tomography
Notes
Acknowledgments
Our cordial thanks to the leading editor of this book, Prof. Jakub Fichna, for the invitation to cooperate in the drafting of this publication.
References
- 1.Böhm B, Schwenk W, Hucke HP, Stock W. Does methodic long-term follow-up affect survival after curative resection of colorectal carcinoma. Dis Colon Rectum. 1993;36:280–6.CrossRefPubMedGoogle Scholar
- 2.Ding P, Liska D, Tang P, Shia J, Saltz L, Goodman K, Downey RJ, Nash GM, Temple LK, Paty PB, et al. Pulmonary recurrence predominates after combined modality therapy for rectal cancer: an original retrospective study. Ann Surg. 2012;256:111–6.CrossRefPubMedGoogle Scholar
- 3.Schmoll HJ, Van Cutsem E, Stein A, Valentini V, Glimelius B, Haustermans K, Nordlinger B, van de Velde CJ, Balmana J, Regula J, Nagtegaal ID, Beets-Tan RG, Arnold D, Ciardiello F, Hoff P, Kerr D, Köhne CH, Labianca R, Price T, Scheithauer W, Sobrero A, Tabernero J, Aderka D, Barroso S, Bodoky G, Douillard JY, El Ghazaly H, Gallardo J, Garin A, Glynne-Jones R, Jordan K, Meshcheryakov A, Papamichail D, Pfeiffer P, Souglakos I, Turhal S, Cervantes A. ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making. Ann Oncol. 2012;23(10):2479–516.CrossRefPubMedGoogle Scholar
- 4.Tjandra JJ, Chan MK. Follow-up after curative resection of colorectal cancer: a meta-analysis. Dis Colon Rectum. 2007;50(11):1783–99.CrossRefPubMedGoogle Scholar
- 5.Renehan AG, Egger M, Saunders MP, O'Dwyer ST. Impact on survival of intensive follow up after curative resection for colorectal cancer: systematic review and meta-analysis of randomised trials. BMJ. 2002;324:813.CrossRefPubMedPubMedCentralGoogle Scholar
- 6.Kahi CJ, Boland CR, Dominitz JA, Giardiello FM, Johnson DA, Kaltenbach T, Lieberman D, Levin TR, Robertson DJ, Rex DK, United States Multi-Society Task Force on Colorectal Cancer. Colonoscopy surveillance after colorectal cancer resection: recommendations of the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology. 2016;150(3):758–768.e11.CrossRefPubMedGoogle Scholar
- 7.Meyerhardt JA, Mangu PB, Flynn PJ, Korde L, Loprinzi CL, Minsky BD, Petrelli NJ, Ryan K, Schrag DH, Wong SL, Benson AB III, American Society of Clinical Oncology. Follow-up care, surveillance protocol, and secondary prevention measures for survivors of colorectal cancer: American Society of Clinical Oncology clinical practice guideline endorsement. J Clin Oncol. 2013;31(35):4465–70.CrossRefPubMedGoogle Scholar
- 8.Steele SR, Chang GJ, Hendren S, Weiser M, Irani J, Buie WD, Rafferty JF, Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons. Practice guideline for the surveillance of patients after curative treatment of colon and rectal cancer. Dis Colon Rectum. 2015;58(8):713–25.CrossRefPubMedGoogle Scholar
- 9.National Institute for Health and Care Excellence guidelines: Colorectal cancer: diagnosis and management. https://www.nice.org.uk/guidance/cg131.
- 10.Mulder SA, Kranse R, Damhuis RA, et al. The incidence and risk factors of metachronous colorectal cancer: an indication for follow-up. Dis Colon Rectum. 2012;55:522–31.CrossRefPubMedGoogle Scholar
- 11.Green RJ, Metlay JP, Propert K, et al. Surveillance for second primary colorectal cancer after adjuvant chemotherapy: an analysis of Intergroup 0089. Ann Intern Med. 2002;136:261–9.CrossRefPubMedGoogle Scholar
- 12.Fisher DA, Jeffreys A, Grambow SC, et al. Mortality and follow-up colonoscopy after colorectal cancer. Am J Gastroenterol. 2003;98:901–6.CrossRefPubMedGoogle Scholar
- 13.Ramsey SD, Howlader N, Etzioni R, et al. Surveillance endoscopy does not improve survival for patients with local and regional stage colo- rectal cancer. Cancer. 2007;109:2222–8.CrossRefPubMedGoogle Scholar
- 14.Rosati G, Ambrosini G, Barni S, Andreoni B, Corradini G, Luchena G, Daniele B, Gaion F, Oliverio G, Duro M, Martignoni G, Pinna N, Sozzi P, Pancera G, Solina G, Pavia G, Pignata S, Johnson F, Labianca R, Apolone G, Zaniboni A, Monteforte M, Negri E, Torri V, Mosconi P, Fossati R, GILDA working group. A randomized trial of intensive versus minimal surveillance of patients with resected Dukes B2-C colorectal carcinoma. Ann Oncol. 2016;27(2):274–80.CrossRefPubMedGoogle Scholar
- 15.Lepage C, Phelip JM, Cany L, Faroux R, Manfredi S, Ain JF, Pezet D, Baconnier M, Deguiral P, Terrebone E, Adenis A, Le Malicot K, Bedenne L, Bouché O. Effect of 5 years of imaging and CEA follow-up to detect recurrence of colorectal cancer: The FFCD PRODIGE 13 randomised phase III trial. Dig Liver Dis. 2015;47(7):529–31.CrossRefPubMedGoogle Scholar
- 16.Nordholm-Carstensen A, Krarup PM, Jorgensen LN, Wille-Jørgensen PA, Harling H. Danish Colorectal Cancer Group. occurrence and survival of synchronous pulmonary metas- tases in colorectal cancer: a nationwide cohort study. Eur J Cancer. 2014;50:447–56.CrossRefPubMedGoogle Scholar
- 17.Mann CD, Metcalfe MS, Neal CP, et al. Role of ultrasonography in the detection of resectable recurrence after hepatectomy for colorectal liver metastases. Br J Surg. 2007;94:1403–7.CrossRefPubMedGoogle Scholar
- 18.Levin B, Lieberman DA, McFarland B, et al. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. CA Cancer J Clin. 2008;58:130–60.CrossRefPubMedGoogle Scholar
- 19.Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. N Engl J Med. 2014;370:1287–97.CrossRefPubMedGoogle Scholar
- 20.Hong YS, Nam BH, Kim KP, Lee JL, Park JO, Park YS, et al. Adjuvant chemotherapy with oxaliplatin/5-fluorouracil/leucovorin (FOLFOX) versus 5-fluorouracil/leucovorin (FL) for rectal cancer patients whose postoperative yp stage 2 or 3 after preoperative chemoradiotherapy: updated results of 3-year disease-free survival from a randomized phase II study (The ADORE). J Clin Oncol. 2014;32(15_suppl):3502.Google Scholar
- 21.Potemski P, Polkowski W, Bujko K, Didkowska J, Guzel Z, Herman R, Łacko A, Olszewski W, Pałucki J, Reguła J. Nowotwory przewodu pokarmowego; 2011. p. 333. Translated from German original: Diagnosis and therapy of gastrointestinal tumors, edition 2011; the translation is published by arrangement with Nora-Verlag GmbH.Google Scholar