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Diabetes Insipidus

  • Catherine Traill
  • Stephen H. HalpernEmail author
Chapter

Abstract

Diabetes insipidus (DI) is characterized by the passage of large amounts of dilute urine and results primarily from either a reduction in the secretion of or impaired response to vasopressin. Vasopressin is a peptide hormone that is synthesized in the hypothalamus before being transported to the posterior pituitary for storage and release. Strategies for medical management that is safe for both mother and fetus will be presented. The anesthetic management of labor and delivery as well as operative deliveries will be discussed.

Keywords

Diabetes insipidus Anesthesia Obstetrical Electrolyte abnormalities Vasopressin 

References

  1. 1.
    Durr JA. Diabetes insipidus in pregnancy. Am J Kidney Dis. 1987;9(4):276–83.CrossRefGoogle Scholar
  2. 2.
    Avanthakrishnan S. Diabetes insipidus in pregnancy: etiology, evaluation and management. Endocr Pract. 2009;15(4):377–82.CrossRefGoogle Scholar
  3. 3.
    Davison JM, Sheills EA, Philips PR, Barron WM, Lindheimer MD. Metabolic clearance of vasopressin and an analogue resistant to vasopressinase in human pregnancy. Am J Physiol. 1993;264(2):F348–53.PubMedGoogle Scholar
  4. 4.
    Ichaliotis SD, Lambrinopoulos TC. Serum oxytocinase in twin pregnancy. Obstet Gynecol. 1965;25(2):270–2.PubMedGoogle Scholar
  5. 5.
    Bichet DG. Hereditary polyuric disorders: new concepts and differential diagnosis. Semin Nephrol. 2006;26(3):224–33.CrossRefGoogle Scholar
  6. 6.
    Aleksandrov N, Audibert F, Bedard MJ, Mahone M, Goffinet F, Kadoch IJ. Gestational diabetes insipidus: a review of an under-diagnosed condition. J Obstet Gynecol Can. 2010;32(3):225–31.CrossRefGoogle Scholar
  7. 7.
    Brewster UC, Hayslett JP. Diabetes insipidus in the third trimester of pregnancy. Obstet Gynecol. 2005;105(5, part 2):1173–6.CrossRefGoogle Scholar
  8. 8.
    Kallen BA, Carlsson SS, Bengtsson BK. Diabetes insipidus and use of desmopressin (Minirin) during pregnancy. Eur J Endocrinol. 1995;132(2):144–6.CrossRefGoogle Scholar
  9. 9.
    Tanifuji Y, Eger EI. Brain sodium, potassium and osmolality: effects of anesthetic requirement. Anesth Analg. 1978;57(4):404–10.CrossRefGoogle Scholar
  10. 10.
    Lacassie HJ, Muir HA, Millar S, Habib AS. Perioperative anesthetic management for Caesarean section of a parturient with gestational diabetes insipidus. Can J Anesth. 2005;52(7):733–6.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of AnesthesiaSunnybrook Health Sciences Centre, University of TorontoTorontoCanada

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